METTL9 (methyltransferase like 9)

2014-11-01  

Identity

HGNC
METTL9
LOCATION
16p12.2
LOCUSID
51108
ALIAS
CGI-81,DREV,DREV1,PAP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 51108
MIM: 609388
HGNC: 24586
Ensembl: ENSG00000197006

Variants:

dbSNP: 51108
ClinVar: 51108
TCGA: ENSG00000197006
COSMIC: METTL9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197006ENST00000358154Q9H1A3
ENSG00000197006ENST00000396014Q9H1A3
ENSG00000197006ENST00000562379H3BTS9
ENSG00000197006ENST00000562961H3BM54
ENSG00000197006ENST00000567404H3BN86
ENSG00000197006ENST00000568826H3BPE9
ENSG00000197006ENST00000569290H3BQD2
ENSG00000197006ENST00000570074H3BRP5
ENSG00000197006ENST00000615720Q8TD49

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
371584562023METTL9 derived circular RNA circ-METTL9 sponges miR-551b-5p to accelerate colorectal cancer progression by upregulating CDK6.2
371584562023METTL9 derived circular RNA circ-METTL9 sponges miR-551b-5p to accelerate colorectal cancer progression by upregulating CDK6.2
335639592021The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes.43
342184072021METTL9 mediated N1-histidine methylation of zinc transporters is required for tumor growth.20
345624502021siRNA screening identifies METTL9 as a histidine Nπ-methyltransferase that targets the proinflammatory protein S100A9.9
335639592021The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes.43
342184072021METTL9 mediated N1-histidine methylation of zinc transporters is required for tumor growth.20
345624502021siRNA screening identifies METTL9 as a histidine Nπ-methyltransferase that targets the proinflammatory protein S100A9.9
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37
168371772006Characterization of the human PAP1 gene and its homologue possible involvement in mouse embryonic development.1
168371772006Characterization of the human PAP1 gene and its homologue possible involvement in mouse embryonic development.1

Citation

Dessen P

METTL9 (methyltransferase like 9)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/68930/mettl9-(methyltransferase-like-9)