Identity
HGNC
LOCATION
17p13.2
LOCUSID
ALIAS
B55,MAP4K6,MINK,YSK2,ZC3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 50488
MIM: 609426
HGNC: 17565
Ensembl: ENSG00000141503
Variants:
dbSNP: 50488
ClinVar: 50488
TCGA: ENSG00000141503
COSMIC: MINK1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Cellular responses to stress | REACTOME | R-HSA-2262752 |
| Cellular Senescence | REACTOME | R-HSA-2559583 |
| Oxidative Stress Induced Senescence | REACTOME | R-HSA-2559580 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38723371 | 2024 | MINK1 deficiency stimulates nucleus pulposus cell pyroptosis and exacerbates intervertebral disc degeneration. | 0 |
| 38723371 | 2024 | MINK1 deficiency stimulates nucleus pulposus cell pyroptosis and exacerbates intervertebral disc degeneration. | 0 |
| 35971817 | 2022 | The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins. | 3 |
| 36012658 | 2022 | Multi-Omic Investigations of a 17-19 Translocation Links MINK1 Disruption to Autism, Epilepsy and Osteoporosis. | 3 |
| 35971817 | 2022 | The serine/threonine kinase MINK1 directly regulates the function of promigratory proteins. | 3 |
| 36012658 | 2022 | Multi-Omic Investigations of a 17-19 Translocation Links MINK1 Disruption to Autism, Epilepsy and Osteoporosis. | 3 |
| 34529319 | 2021 | LncRNA SNHG14 contributes to proinflammatory cytokine production in rheumatoid arthritis via the regulation of the miR-17-5p/MINK1-JNK pathway. | 11 |
| 34529319 | 2021 | LncRNA SNHG14 contributes to proinflammatory cytokine production in rheumatoid arthritis via the regulation of the miR-17-5p/MINK1-JNK pathway. | 11 |
| 31160382 | 2019 | Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics. | 4 |
| 31160382 | 2019 | Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics. | 4 |
| 25747578 | 2015 | The role of Misshapen NCK-related kinase (MINK), a novel Ste20 family kinase, in the IRES-mediated protein translation of human enterovirus 71. | 24 |
| 25747578 | 2015 | The role of Misshapen NCK-related kinase (MINK), a novel Ste20 family kinase, in the IRES-mediated protein translation of human enterovirus 71. | 24 |
| 22037766 | 2012 | Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation. | 20 |
| 22665485 | 2012 | Misshapen-like kinase 1 (MINK1) is a novel component of striatin-interacting phosphatase and kinase (STRIPAK) and is required for the completion of cytokinesis. | 36 |
| 22037766 | 2012 | Mink1 regulates β-catenin-independent Wnt signaling via Prickle phosphorylation. | 20 |
Citation
Dessen P
MINK1 (misshapen like kinase 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/68989/mink1-(misshapen-like-kinase-1)
