Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55586
MIM: 606774
HGNC: 14522
Ensembl: ENSG00000100253
Variants:
dbSNP: 55586
ClinVar: 55586
TCGA: ENSG00000100253
COSMIC: MIOX
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000100253 | ENST00000216075 | Q9UGB7 |
| ENSG00000100253 | ENST00000395732 | A6PVH2 |
| ENSG00000100253 | ENST00000395733 | Q9UGB7 |
| ENSG00000100253 | ENST00000451761 | A6PVH4 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Ascorbate and aldarate metabolism | KEGG | ko00053 |
| Inositol phosphate metabolism | KEGG | ko00562 |
| Ascorbate and aldarate metabolism | KEGG | hsa00053 |
| Inositol phosphate metabolism | KEGG | hsa00562 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37249295 | 2023 | Myo-inositol oxygenase (MIOX) accelerated inflammation in the model of infection-induced cardiac dysfunction by NLRP3 inflammasome. | 0 |
| 37977044 | 2023 | MIOX inhibits autophagy to regulate the ROS -driven inhibition of STAT3/c-Myc-mediated epithelial-mesenchymal transition in clear cell renal cell carcinoma. | 1 |
| 37249295 | 2023 | Myo-inositol oxygenase (MIOX) accelerated inflammation in the model of infection-induced cardiac dysfunction by NLRP3 inflammasome. | 0 |
| 37977044 | 2023 | MIOX inhibits autophagy to regulate the ROS -driven inhibition of STAT3/c-Myc-mediated epithelial-mesenchymal transition in clear cell renal cell carcinoma. | 1 |
| 35338333 | 2022 | Long noncoding RNA NEAT1 promotes ferroptosis by modulating the miR-362-3p/MIOX axis as a ceRNA. | 68 |
| 35338333 | 2022 | Long noncoding RNA NEAT1 promotes ferroptosis by modulating the miR-362-3p/MIOX axis as a ceRNA. | 68 |
| 32169892 | 2020 | Myo-inositol Oxygenase (MIOX) Overexpression Drives the Progression of Renal Tubulointerstitial Injury in Diabetes. | 21 |
| 32169892 | 2020 | Myo-inositol Oxygenase (MIOX) Overexpression Drives the Progression of Renal Tubulointerstitial Injury in Diabetes. | 21 |
| 30539651 | 2019 | Myo-inositol oxygenase accentuates renal tubular injury initiated by endoplasmic reticulum stress. | 9 |
| 30539651 | 2019 | Myo-inositol oxygenase accentuates renal tubular injury initiated by endoplasmic reticulum stress. | 9 |
| 29187000 | 2018 | Does myo-inositol oxygenase, the only enzyme to catalyze myo-inositol in vivo, play a role in the etiology of polycystic ovarian syndrome? | 0 |
| 30504713 | 2018 | The Kidney Specific Protein myo-Inositol Oxygenase, a Potential Biomarker for Diabetic Nephropathy. | 4 |
| 29187000 | 2018 | Does myo-inositol oxygenase, the only enzyme to catalyze myo-inositol in vivo, play a role in the etiology of polycystic ovarian syndrome? | 0 |
| 30504713 | 2018 | The Kidney Specific Protein myo-Inositol Oxygenase, a Potential Biomarker for Diabetic Nephropathy. | 4 |
| 28208054 | 2017 | High Glucose-Induced Hypomethylation Promotes Binding of Sp-1 to Myo-Inositol Oxygenase: Implication in the Pathobiology of Diabetic Tubulopathy. | 21 |
Citation
Dessen P
MIOX (myo-inositol oxygenase)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/68993/miox-(myo-inositol-oxygenase)
