Identity
HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
GEF1,IMD62,LBCL2,LSC,P115-RHOGEF,SUB1.5
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9138
MIM: 601855
HGNC: 681
Ensembl: ENSG00000076928
Variants:
dbSNP: 9138
ClinVar: 9138
TCGA: ENSG00000076928
COSMIC: ARHGEF1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35037717 | 2022 | Integrative multiomics and in silico analysis revealed the role of ARHGEF1 and its screened antagonist in mild and severe COVID-19 patients. | 4 |
| 35037717 | 2022 | Integrative multiomics and in silico analysis revealed the role of ARHGEF1 and its screened antagonist in mild and severe COVID-19 patients. | 4 |
| 32808262 | 2021 | Identification of Rho GEF and RhoA Activation by Pull-Down Assays. | 2 |
| 32808262 | 2021 | Identification of Rho GEF and RhoA Activation by Pull-Down Assays. | 2 |
| 29071730 | 2018 | Transforming growth factor-β enhances Rho-kinase activity and contraction in airway smooth muscle via the nucleotide exchange factor ARHGEF1. | 17 |
| 29071730 | 2018 | Transforming growth factor-β enhances Rho-kinase activity and contraction in airway smooth muscle via the nucleotide exchange factor ARHGEF1. | 17 |
| 28179147 | 2017 | Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF. | 3 |
| 28655771 | 2017 | p115 RhoGEF activates the Rac1 GTPase signaling cascade in MCP1 chemokine-induced vascular smooth muscle cell migration and proliferation. | 16 |
| 28179147 | 2017 | Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF. | 3 |
| 28655771 | 2017 | p115 RhoGEF activates the Rac1 GTPase signaling cascade in MCP1 chemokine-induced vascular smooth muscle cell migration and proliferation. | 16 |
| 26911374 | 2016 | Cdc42 and Rac1 activity is reduced in human pheochromocytoma and correlates with FARP1 and ARHGEF1 expression. | 16 |
| 26911374 | 2016 | Cdc42 and Rac1 activity is reduced in human pheochromocytoma and correlates with FARP1 and ARHGEF1 expression. | 16 |
| 25916117 | 2015 | [Under hypoxia condition contactin-1 regulates migration of MKN45 cells through RhoA pathway]. | 1 |
| 25916117 | 2015 | [Under hypoxia condition contactin-1 regulates migration of MKN45 cells through RhoA pathway]. | 1 |
| 24465552 | 2014 | A novel role for p115RhoGEF in regulation of epithelial plasticity. | 7 |
Citation
Dessen P
ARHGEF1 (Rho guanine nucleotide exchange factor 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/698/arhgef1-(rho-guanine-nucleotide-exchange-factor-1)
