Identity
HGNC
LOCATION
14q23.1
LOCUSID
ALIAS
RBBP-1,RBBP1,RBP-1,RBP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5926
MIM: 180201
HGNC: 9885
Ensembl: ENSG00000032219
Variants:
dbSNP: 5926
ClinVar: 5926
TCGA: ENSG00000032219
COSMIC: ARID4A
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
| HDACs deacetylate histones | REACTOME | R-HSA-3214815 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35365808 | 2022 | A novel heterozygous missense variant of the ARID4A gene identified in Han Chinese families with schizophrenia-diagnosed siblings that interferes with DNA-binding activity. | 0 |
| 35365808 | 2022 | A novel heterozygous missense variant of the ARID4A gene identified in Han Chinese families with schizophrenia-diagnosed siblings that interferes with DNA-binding activity. | 0 |
| 34506790 | 2021 | Structural Insight into Chromatin Recognition by Multiple Domains of the Tumor Suppressor RBBP1. | 3 |
| 34506790 | 2021 | Structural Insight into Chromatin Recognition by Multiple Domains of the Tumor Suppressor RBBP1. | 3 |
| 29408527 | 2018 | Crystal structure of chromo barrel domain of RBBP1. | 1 |
| 29797600 | 2018 | Downregulation of ARID4A and ARID4B promote tumor progression and directly regulated by microRNA-30d in patient with prostate cancer. | 8 |
| 29408527 | 2018 | Crystal structure of chromo barrel domain of RBBP1. | 1 |
| 29797600 | 2018 | Downregulation of ARID4A and ARID4B promote tumor progression and directly regulated by microRNA-30d in patient with prostate cancer. | 8 |
| 24379399 | 2014 | Retinoblastoma-binding protein 1 has an interdigitated double Tudor domain with DNA binding activity. | 6 |
| 24379399 | 2014 | Retinoblastoma-binding protein 1 has an interdigitated double Tudor domain with DNA binding activity. | 6 |
| 22247551 | 2012 | Structural insight into recognition of methylated histone tails by retinoblastoma-binding protein 1. | 10 |
| 22732186 | 2012 | Reactive oxygen species mediate microRNA-302 regulation of AT-rich interacting domain 4a and C-C motif ligand 5 expression during transitions between quiescence and proliferation. | 5 |
| 22247551 | 2012 | Structural insight into recognition of methylated histone tails by retinoblastoma-binding protein 1. | 10 |
| 22732186 | 2012 | Reactive oxygen species mediate microRNA-302 regulation of AT-rich interacting domain 4a and C-C motif ligand 5 expression during transitions between quiescence and proliferation. | 5 |
| 18211900 | 2008 | Alterations of BRMS1-ARID4A interaction modify gene expression but still suppress metastasis in human breast cancer cells. | 39 |
Citation
Dessen P
ARID4A (AT-rich interaction domain 4A)
Atlas Genet Cytogenet Oncol Haematol. 2003-02-01
Online version: http://atlasgeneticsoncology.org/gene/703
