Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79003
MIM: 609178
HGNC: 24967
Ensembl: ENSG00000167842
Variants:
dbSNP: 79003
ClinVar: 79003
TCGA: ENSG00000167842
COSMIC: MIS12
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33035345 | 2020 | METTL3 counteracts premature aging via m6A-dependent stabilization of MIS12 mRNA. | 66 |
| 33035345 | 2020 | METTL3 counteracts premature aging via m6A-dependent stabilization of MIS12 mRNA. | 66 |
| 28012276 | 2016 | Molecular basis of outer kinetochore assembly on CENP-T. | 70 |
| 28012276 | 2016 | Molecular basis of outer kinetochore assembly on CENP-T. | 70 |
| 25601404 | 2015 | Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochores. | 68 |
| 25601404 | 2015 | Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochores. | 68 |
| 24530301 | 2014 | Modular assembly of RWD domains on the Mis12 complex underlies outer kinetochore organization. | 76 |
| 24530301 | 2014 | Modular assembly of RWD domains on the Mis12 complex underlies outer kinetochore organization. | 76 |
| 21353556 | 2011 | Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore. | 146 |
| 21353556 | 2011 | Direct binding of Cenp-C to the Mis12 complex joins the inner and outer kinetochore. | 146 |
| 20404110 | 2010 | Hsp90-Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites. | 38 |
| 20404110 | 2010 | Hsp90-Sgt1 and Skp1 target human Mis12 complexes to ensure efficient formation of kinetochore-microtubule binding sites. | 38 |
| 16585270 | 2006 | The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. | 109 |
| 16585270 | 2006 | The human Mis12 complex is required for kinetochore assembly and proper chromosome segregation. | 109 |
| 12515822 | 2003 | Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway. | 105 |
Citation
Dessen P
MIS12 (MIS12 kinetochore complex component)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/70322/mis12-(mis12-kinetochore-complex-component)
