MISP (mitotic spindle positioning)

2014-11-01  

Identity

HGNC
MISP
LOCATION
19p13.3
LOCUSID
126353
ALIAS
C19orf21,MISP1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 126353
MIM: 615289
HGNC: 27000
Ensembl: ENSG00000099812

Variants:

dbSNP: 126353
ClinVar: 126353
TCGA: ENSG00000099812
COSMIC: MISP

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000099812ENST00000215582Q8IVT2

Expression (GTEx)

0
50
100
150
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
380573582024PLK1 and its substrate MISP facilitate intrahepatic cholangiocarcinoma progression by promoting lymphatic invasion and impairing E-cadherin adherens junctions.1
383301172024Plants distinguish different photoperiods to independently control seasonal flowering and growth.2
385888082024Mitotic spindle positioning protein (MISP) preferentially binds to aged F-actin.0
380573582024PLK1 and its substrate MISP facilitate intrahepatic cholangiocarcinoma progression by promoting lymphatic invasion and impairing E-cadherin adherens junctions.1
383301172024Plants distinguish different photoperiods to independently control seasonal flowering and growth.2
385888082024Mitotic spindle positioning protein (MISP) preferentially binds to aged F-actin.0
340237772021Modulation of actin-binding and -bundling activities of MISP/Caprice by multiple phosphorylation.1
340237772021Modulation of actin-binding and -bundling activities of MISP/Caprice by multiple phosphorylation.1
296697402018Activated ezrin controls MISP levels to ensure correct NuMA polarization and spindle orientation.14
296697402018Activated ezrin controls MISP levels to ensure correct NuMA polarization and spindle orientation.14
244759242014Caprice/MISP is a novel F-actin bundling protein critical for actin-based cytoskeletal reorganizations.11
244759242014Caprice/MISP is a novel F-actin bundling protein critical for actin-based cytoskeletal reorganizations.11
244759242014Caprice/MISP is a novel F-actin bundling protein critical for actin-based cytoskeletal reorganizations.11
244759242014Caprice/MISP is a novel F-actin bundling protein critical for actin-based cytoskeletal reorganizations.11
235090692013MISP is a novel Plk1 substrate required for proper spindle orientation and mitotic progression.40

Citation

Dessen P

MISP (mitotic spindle positioning)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70325/misp-(mitotic-spindle-positioning)