Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23209
MIM: 605908
HGNC: 17082
Ensembl: ENSG00000100427
Variants:
dbSNP: 23209
ClinVar: 23209
TCGA: ENSG00000100427
COSMIC: MLC1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37821359 | 2024 | MLC1 Overexpression Inhibits Tumor Progression through PI3K/AKT Signal Pathway in Prostate Cancer. | 0 |
| 38141856 | 2024 | Megalencephalic leukoencephalopathy with subcortical cysts protein-1: A new calcium-sensitive protein functionally activated by endoplasmic reticulum calcium release and calmodulin binding in astrocytes. | 0 |
| 37821359 | 2024 | MLC1 Overexpression Inhibits Tumor Progression through PI3K/AKT Signal Pathway in Prostate Cancer. | 0 |
| 38141856 | 2024 | Megalencephalic leukoencephalopathy with subcortical cysts protein-1: A new calcium-sensitive protein functionally activated by endoplasmic reticulum calcium release and calmodulin binding in astrocytes. | 0 |
| 34918859 | 2022 | A homozygous missense variant in the MLC1 gene underlies megalencephalic leukoencephalopathy with subcortical cysts in large kindred: Heterozygous carriers show seizure and mild motor function deterioration. | 2 |
| 35440380 | 2022 | Prevalent MLC1 mutation causing autosomal recessive megalencephalic leukoencephalopathy in consanguineous Palestinian families. | 2 |
| 34918859 | 2022 | A homozygous missense variant in the MLC1 gene underlies megalencephalic leukoencephalopathy with subcortical cysts in large kindred: Heterozygous carriers show seizure and mild motor function deterioration. | 2 |
| 35440380 | 2022 | Prevalent MLC1 mutation causing autosomal recessive megalencephalic leukoencephalopathy in consanguineous Palestinian families. | 2 |
| 34847774 | 2021 | Transmembrane topology and oligomeric nature of an astrocytic membrane protein, MLC1. | 3 |
| 34847774 | 2021 | Transmembrane topology and oligomeric nature of an astrocytic membrane protein, MLC1. | 3 |
| 31960914 | 2020 | Structural basis for the dominant or recessive character of GLIALCAM mutations found in leukodystrophies. | 8 |
| 32209057 | 2020 | Novel variants underlying autosomal recessive intellectual disability in Pakistani consanguineous families. | 2 |
| 32521795 | 2020 | Megalencephalic Leukoencephalopathy with Subcortical Cysts Disease-Linked MLC1 Protein Favors Gap-Junction Intercellular Communication by Regulating Connexin 43 Trafficking in Astrocytes. | 11 |
| 33040087 | 2020 | Megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1) promotes glioblastoma cell invasion in the brain microenvironment. | 8 |
| 31960914 | 2020 | Structural basis for the dominant or recessive character of GLIALCAM mutations found in leukodystrophies. | 8 |
Citation
Dessen P
MLC1 (modulator of VRAC current 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/70337/mlc1-(modulator-of-vrac-current-1)
