MON2 (MON2 homolog, regulator of endosome-to-Golgi trafficking)

2014-11-01  

Identity

HGNC
MON2
LOCATION
12q14.1
LOCUSID
23041
ALIAS
-
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 23041
MIM: 616822
HGNC: 29177
Ensembl: ENSG00000061987

Variants:

dbSNP: 23041
ClinVar: 23041
TCGA: ENSG00000061987
COSMIC: MON2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000061987ENST00000393629Q7Z3U7
ENSG00000061987ENST00000393630Q7Z3U7
ENSG00000061987ENST00000546600Q7Z3U7
ENSG00000061987ENST00000547095F8VZV6
ENSG00000061987ENST00000549286F8VQS2
ENSG00000061987ENST00000552115F8VZV1
ENSG00000061987ENST00000552738Q7Z3U7
ENSG00000061987ENST00000641654A0A286YFF8

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
325729122020MicroRNA-133a-5p inhibiting metastatic capacity of renal clear cell carcinoma through regulating MON2.1
325729122020MicroRNA-133a-5p inhibiting metastatic capacity of renal clear cell carcinoma through regulating MON2.1
302139402018SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.37
302139402018SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion.37
242853432013Mammalian Mon2/Ysl2 regulates endosome-to-Golgi trafficking but possesses no guanine nucleotide exchange activity toward Arl1 GTPase.15
242853432013Mammalian Mon2/Ysl2 regulates endosome-to-Golgi trafficking but possesses no guanine nucleotide exchange activity toward Arl1 GTPase.15
214508272011The cellular factors Vps18 and Mon2 are required for efficient production of infectious HIV-1 particles.11
214508272011The cellular factors Vps18 and Mon2 are required for efficient production of infectious HIV-1 particles.11
184183882008Yeast and human Ysl2p/hMon2 interact with Gga adaptors and mediate their subcellular distribution.14
184183882008Yeast and human Ysl2p/hMon2 interact with Gga adaptors and mediate their subcellular distribution.14

Citation

Dessen P

MON2 (MON2 homolog, regulator of endosome-to-Golgi trafficking)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70370/mon2-(mon2-homolog-regulator-of-endosome-to-golgi-trafficking)