MORC1 (MORC family CW-type zinc finger 1)

2014-11-01  

Identity

HGNC
MORC1
LOCATION
3q13.13
LOCUSID
27136
ALIAS
CT33,MORC,ZCW6
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 27136
MIM: 603205
HGNC: 7198
Ensembl: ENSG00000114487

Variants:

dbSNP: 27136
ClinVar: 27136
TCGA: ENSG00000114487
COSMIC: MORC1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000114487ENST00000232603Q86VD1
ENSG00000114487ENST00000483760Q86VD1

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
334011282021MORC1 methylation and BDI are associated with microstructural features of the hippocampus and medial prefrontal cortex.7
334011282021MORC1 methylation and BDI are associated with microstructural features of the hippocampus and medial prefrontal cortex.7
316830972020Investigation of MORC1 DNA methylation as biomarker of early life stress and depressive symptoms.6
316830972020Investigation of MORC1 DNA methylation as biomarker of early life stress and depressive symptoms.6
298905062018Methylation of MORC1: A possible biomarker for depression?6
298905062018Methylation of MORC1: A possible biomarker for depression?6
251580042014MORC1 exhibits cross-species differential methylation in association with early life stress as well as genome-wide association with MDD.39
251580042014MORC1 exhibits cross-species differential methylation in association with early life stress as well as genome-wide association with MDD.39
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

MORC1 (MORC family CW-type zinc finger 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70372/morc1-(morc-family-cw-type-zinc-finger-1)