MRGPRX1 (MAS related GPR family member X1)

2014-11-01  

Identity

HGNC
LOCATION
11p15.1
LOCUSID
ALIAS
GPCR,MGRG2,MRGX1,SNSR4

Other Information

Locus ID:

NCBI: 259249
MIM: 607227
HGNC: 17962
Ensembl: ENSG00000170255

Variants:

dbSNP: 259249
ClinVar: 259249
TCGA: ENSG00000170255
COSMIC: MRGPRX1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000170255ENST00000302797Q96LB2
ENSG00000170255ENST00000302797W8W3P5
ENSG00000170255ENST00000526914A0A494C1K4

Expression (GTEx)

0
1

References

Pubmed IDYearTitleCitations
373477492023Mechanism of agonist-induced activation of the human itch receptor MRGPRX1.1
375918892023Ligand recognition and G protein coupling of the human itch receptor MRGPRX1.1
373477492023Mechanism of agonist-induced activation of the human itch receptor MRGPRX1.1
375918892023Ligand recognition and G protein coupling of the human itch receptor MRGPRX1.1
338915442021Pruriception and neuronal coding in nociceptor subtypes in human and nonhuman primates.19
338915442021Pruriception and neuronal coding in nociceptor subtypes in human and nonhuman primates.19
311198282019Mas-related G protein-coupled receptor C11 (Mrgprc11) induces visceral hypersensitivity in the mouse colon: A novel target in gut nociception?7
313504332019BAM8-22 and its receptor MRGPRX1 may attribute to cholestatic pruritus.11
311198282019Mas-related G protein-coupled receptor C11 (Mrgprc11) induces visceral hypersensitivity in the mouse colon: A novel target in gut nociception?7
313504332019BAM8-22 and its receptor MRGPRX1 may attribute to cholestatic pruritus.11
289881172018Mas-Related G-Protein Coupled Receptors and Cowhage-Induced Itch.13
289881172018Mas-Related G-Protein Coupled Receptors and Cowhage-Induced Itch.13
282235162017Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain.37
287687712017Activation of mas-related G-protein-coupled receptors by the house dust mite cysteine protease Der p1 provides a new mechanism linking allergy and inflammation.13
282235162017Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain.37

Citation

Dessen P

MRGPRX1 (MAS related GPR family member X1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70415/mrgprx1-(mas-related-gpr-family-member-x1)