MRGPRX4 (MAS related GPR family member X4)

2014-11-01  

Identity

HGNC
LOCATION
11p15.1
LOCUSID
ALIAS
GPCR,MRGX4,SNSR6

Other Information

Locus ID:

NCBI: 117196
MIM: 607230
HGNC: 17617
Ensembl: ENSG00000179817

Variants:

dbSNP: 117196
ClinVar: 117196
TCGA: ENSG00000179817
COSMIC: MRGPRX4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000179817ENST00000314254Q96LA9

Expression (GTEx)

0
1

References

Pubmed IDYearTitleCitations
387181322024MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model.0
387181322024MRGPRX4 mediates phospho-drug-associated pruritus in a humanized mouse model.0
370035052023Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins.3
370035052023Itch receptor MRGPRX4 interacts with the receptor activity-modifying proteins.3
341619942021MRGPRX4 in Cholestatic Pruritus.3
347898742021Structure, function and pharmacology of human itch GPCRs.63
341619942021MRGPRX4 in Cholestatic Pruritus.3
347898742021Structure, function and pharmacology of human itch GPCRs.63
307685912019An African-specific haplotype in MRGPRX4 is associated with menthol cigarette smoking.15
310684642019MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus.47
315006982019MRGPRX4 is a bile acid receptor for human cholestatic itch.42
307685912019An African-specific haplotype in MRGPRX4 is associated with menthol cigarette smoking.15
310684642019MRGPRX4 is a G protein-coupled receptor activated by bile acids that may contribute to cholestatic pruritus.47
315006982019MRGPRX4 is a bile acid receptor for human cholestatic itch.42
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

MRGPRX4 (MAS related GPR family member X4)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70417/mrgprx4-(mas-related-gpr-family-member-x4)