Identity
HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
5c5-2,L12mt,MRP-L31/34,MRPL7,MRPL7/L12,RPML12
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6182
MIM: 602375
HGNC: 10378
Ensembl: ENSG00000262814
Variants:
dbSNP: 6182
ClinVar: 6182
TCGA: ENSG00000262814
COSMIC: MRPL12
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000262814 | ENST00000333676 | P52815 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38104924 | 2024 | Mitochondrial ribosomal protein L12 potentiates hepatocellular carcinoma by regulating mitochondrial biogenesis and metabolic reprogramming. | 1 |
| 38129673 | 2024 | The m6A Reader YTHDC2 Suppresses Lung Adenocarcinoma Tumorigenesis by Destabilizing MRPL12. | 1 |
| 38146092 | 2024 | The role of lysine acetylation in the function of mitochondrial ribosomal protein L12. | 0 |
| 38104924 | 2024 | Mitochondrial ribosomal protein L12 potentiates hepatocellular carcinoma by regulating mitochondrial biogenesis and metabolic reprogramming. | 1 |
| 38129673 | 2024 | The m6A Reader YTHDC2 Suppresses Lung Adenocarcinoma Tumorigenesis by Destabilizing MRPL12. | 1 |
| 38146092 | 2024 | The role of lysine acetylation in the function of mitochondrial ribosomal protein L12. | 0 |
| 36769082 | 2023 | MRPL12 Acts as A Novel Prognostic Biomarker Involved in Immune Cell Infiltration and Tumor Progression of Lung Adenocarcinoma. | 2 |
| 37526061 | 2023 | CUL3 induces mitochondrial dysfunction via MRPL12 ubiquitination in renal tubular epithelial cells. | 1 |
| 36769082 | 2023 | MRPL12 Acts as A Novel Prognostic Biomarker Involved in Immune Cell Infiltration and Tumor Progression of Lung Adenocarcinoma. | 2 |
| 37526061 | 2023 | CUL3 induces mitochondrial dysfunction via MRPL12 ubiquitination in renal tubular epithelial cells. | 1 |
| 33444714 | 2021 | Transcription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney disease. | 11 |
| 33444714 | 2021 | Transcription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney disease. | 11 |
| 26586915 | 2016 | Mitochondrial Ribosomal Protein L12 Is Required for POLRMT Stability and Exists as Two Forms Generated by Alternative Proteolysis during Import. | 19 |
| 26586915 | 2016 | Mitochondrial Ribosomal Protein L12 Is Required for POLRMT Stability and Exists as Two Forms Generated by Alternative Proteolysis during Import. | 19 |
| 23603806 | 2013 | Mutations in mitochondrial ribosomal protein MRPL12 leads to growth retardation, neurological deterioration and mitochondrial translation deficiency. | 49 |
Citation
Dessen P
MRPL12 (mitochondrial ribosomal protein L12)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/70434/mrpl12-(mitochondrial-ribosomal-protein-l12)
