MRPL19 (mitochondrial ribosomal protein L19)

2014-11-01  

Identity

HGNC
LOCATION
2p12
LOCUSID
ALIAS
L19mt,MRP-L15,MRP-L19,MRPL15,RLX1,RPML15
FUSION GENES

Other Information

Locus ID:

NCBI: 9801
MIM: 611832
HGNC: 14052
Ensembl: ENSG00000115364

Variants:

dbSNP: 9801
ClinVar: 9801
TCGA: ENSG00000115364
COSMIC: MRPL19

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000115364ENST00000358788A0A0A0MRF4
ENSG00000115364ENST00000393909P49406
ENSG00000115364ENST00000409374P49406
ENSG00000115364ENST00000453233H7C2J0
ENSG00000115364ENST00000476622S4R3W9
ENSG00000115364ENST00000492255S4R455

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
RibosomeKEGGko03010
RibosomeKEGGhsa03010
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
295669792018Beyond genes: A systematic review of environmental risk factors in specific reading disorder.11
295669792018Beyond genes: A systematic review of environmental risk factors in specific reading disorder.11
254483222015Language impairment and dyslexia genes influence language skills in children with autism spectrum disorders.23
254483222015Language impairment and dyslexia genes influence language skills in children with autism spectrum disorders.23
239548682013Lack of association between genetic polymorphisms in ROBO1, MRPL19/C2ORF3 and THEM2 with developmental dyslexia.3
239548682013Lack of association between genetic polymorphisms in ROBO1, MRPL19/C2ORF3 and THEM2 with developmental dyslexia.3
208462472011Analysis of dyslexia candidate genes in the Raine cohort representing the general Australian population.27
208462472011Analysis of dyslexia candidate genes in the Raine cohort representing the general Australian population.27
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
173098792007A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia.49
173098792007A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia.49
173098792007A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia.49

Citation

Dessen P

MRPL19 (mitochondrial ribosomal protein L19)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70441/mrpl19-(mitochondrial-ribosomal-protein-l19)