MRPS23 (mitochondrial ribosomal protein S23)

2014-11-01  

Identity

HGNC
LOCATION
17q22
LOCUSID
ALIAS
CGI-138,COXPD46,HSPC329,MRP-S23
FUSION GENES

Other Information

Locus ID:

NCBI: 51649
MIM: 611985
HGNC: 14509
Ensembl: ENSG00000181610

Variants:

dbSNP: 51649
ClinVar: 51649
TCGA: ENSG00000181610
COSMIC: MRPS23

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181610ENST00000313608Q9Y3D9
ENSG00000181610ENST00000578444J3QLR8
ENSG00000181610ENST00000579380J3QLC1

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation initiationREACTOMER-HSA-5368286
Mitochondrial translation elongationREACTOMER-HSA-5389840
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
383010442024MRPS23 is a novel prognostic biomarker and promotes glioma progression.0
383010442024MRPS23 is a novel prognostic biomarker and promotes glioma progression.0
380869842023Genetic, metabolic and clinical delineation of an MRPS23-associated mitochondrial disorder.1
380869842023Genetic, metabolic and clinical delineation of an MRPS23-associated mitochondrial disorder.1
359628482022Mitochondrial ribosomal small subunit (MRPS) MRPS23 protein-protein interaction reveals phosphorylation by CDK11-p58 affecting cell proliferation and knockdown of MRPS23 sensitizes breast cancer cells to CDK1 inhibitors.1
359628482022Mitochondrial ribosomal small subunit (MRPS) MRPS23 protein-protein interaction reveals phosphorylation by CDK11-p58 affecting cell proliferation and knockdown of MRPS23 sensitizes breast cancer cells to CDK1 inhibitors.1
339273502021Arginine and lysine methylation of MRPS23 promotes breast cancer metastasis through regulating OXPHOS.18
339643762021Mitochondrial ribosomal small subunit proteins (MRPS) MRPS6 and MRPS23 show dysregulation in breast cancer affecting tumorigenic cellular processes.8
339273502021Arginine and lysine methylation of MRPS23 promotes breast cancer metastasis through regulating OXPHOS.18
339643762021Mitochondrial ribosomal small subunit proteins (MRPS) MRPS6 and MRPS23 show dysregulation in breast cancer affecting tumorigenic cellular processes.8
319503852020MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes.9
319503852020MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes.9
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78

Citation

Dessen P

MRPS23 (mitochondrial ribosomal protein S23)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70481/mrps23-(mitochondrial-ribosomal-protein-s23)