MRRF (mitochondrial ribosome recycling factor)

2014-11-01  

Identity

HGNC
MRRF
LOCATION
9q33.2
LOCUSID
92399
ALIAS
MRFF,MTRRF,RRF
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 92399
MIM: 604602
HGNC: 7234
Ensembl: ENSG00000148187

Variants:

dbSNP: 92399
ClinVar: 92399
TCGA: ENSG00000148187
COSMIC: MRRF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148187ENST00000297908Q96E11
ENSG00000148187ENST00000344641Q96E11
ENSG00000148187ENST00000373723Q96E11
ENSG00000148187ENST00000373729Q96E11
ENSG00000148187ENST00000394315Q96E11
ENSG00000148187ENST00000441707X6RDS5
ENSG00000148187ENST00000467864Q96E11
ENSG00000148187ENST00000470366Q96E11
ENSG00000148187ENST00000470366A0A024R855
ENSG00000148187ENST00000489572Q96E11
ENSG00000148187ENST00000489572A0A024R855

Expression (GTEx)

0
5
10
15
20
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Organelle biogenesis and maintenanceREACTOMER-HSA-1852241
Mitochondrial translationREACTOMER-HSA-5368287
Mitochondrial translation terminationREACTOMER-HSA-5419276

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
197167932009EF-G2mt is an exclusive recycling factor in mammalian mitochondrial protein synthesis.48
197167932009EF-G2mt is an exclusive recycling factor in mammalian mitochondrial protein synthesis.48
187828332008The human mitochondrial ribosome recycling factor is essential for cell viability.59
187828332008The human mitochondrial ribosome recycling factor is essential for cell viability.59

Citation

Dessen P

MRRF (mitochondrial ribosome recycling factor)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70495/