Identity
HGNC
LOCATION
Xp22.2
LOCUSID
ALIAS
MRSXBA,MRXS36,MRXSBA,MSL3L1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10943
MIM: 300609
HGNC: 7370
Ensembl: ENSG00000005302
Variants:
dbSNP: 10943
ClinVar: 10943
TCGA: ENSG00000005302
COSMIC: MSL3
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
| HATs acetylate histones | REACTOME | R-HSA-3214847 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33173220 | 2021 | Defining the genotypic and phenotypic spectrum of X-linked MSL3-related disorder. | 3 |
| 33173220 | 2021 | Defining the genotypic and phenotypic spectrum of X-linked MSL3-related disorder. | 3 |
| 30224647 | 2018 | De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation. | 19 |
| 30224647 | 2018 | De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation. | 19 |
| 20943666 | 2010 | Structural and biochemical studies on the chromo-barrel domain of male specific lethal 3 (MSL3) reveal a binding preference for mono- or dimethyllysine 20 on histone H4. | 23 |
| 20943666 | 2010 | Structural and biochemical studies on the chromo-barrel domain of male specific lethal 3 (MSL3) reveal a binding preference for mono- or dimethyllysine 20 on histone H4. | 23 |
| 16227571 | 2005 | A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16. | 170 |
| 16227571 | 2005 | A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16. | 170 |
Citation
Dessen P
MSL3 (MSL complex subunit 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/70519/msl3-(msl-complex-subunit-3)
