Identity
HGNC
LOCATION
20q13.33
LOCUSID
ALIAS
GTPBP5,ObgH1,dJ1005F21.2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26164
MIM: 610919
HGNC: 16239
Ensembl: ENSG00000101181
Variants:
dbSNP: 26164
ClinVar: 26164
TCGA: ENSG00000101181
COSMIC: MTG2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101181 | ENST00000370823 | Q9H4K7 |
| ENSG00000101181 | ENST00000448254 | Q5JXJ0 |
| ENSG00000101181 | ENST00000467101 | B4DRC1 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33283228 | 2021 | Human GTPBP5 is involved in the late stage of mitoribosome large subunit assembly. | 13 |
| 33283228 | 2021 | Human GTPBP5 is involved in the late stage of mitoribosome large subunit assembly. | 13 |
| 32652011 | 2020 | Human GTPBP5 (MTG2) fuels mitoribosome large subunit maturation by facilitating 16S rRNA methylation. | 23 |
| 32652011 | 2020 | Human GTPBP5 (MTG2) fuels mitoribosome large subunit maturation by facilitating 16S rRNA methylation. | 23 |
| 23396448 | 2013 | Human G-proteins, ObgH1 and Mtg1, associate with the large mitochondrial ribosome subunit and are involved in translation and assembly of respiratory complexes. | 34 |
| 23396448 | 2013 | Human G-proteins, ObgH1 and Mtg1, associate with the large mitochondrial ribosome subunit and are involved in translation and assembly of respiratory complexes. | 34 |
| 21608104 | 2011 | De novo deletion of chromosome 20q13.33 in a patient with tracheo-esophageal fistula, cardiac defects and genitourinary anomalies implicates GTPBP5 as a candidate gene. | 16 |
| 21608104 | 2011 | De novo deletion of chromosome 20q13.33 in a patient with tracheo-esophageal fistula, cardiac defects and genitourinary anomalies implicates GTPBP5 as a candidate gene. | 16 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 17054726 | 2006 | Human small G proteins, ObgH1, and ObgH2, participate in the maintenance of mitochondria and nucleolar architectures. | 22 |
| 17054726 | 2006 | Human small G proteins, ObgH1, and ObgH2, participate in the maintenance of mitochondria and nucleolar architectures. | 22 |
Citation
Dessen P
MTG2 (mitochondrial ribosome associated GTPase 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/70546/mtg2-(mitochondrial-ribosome-associated-gtpase-2)
