Identity
HGNC
LOCATION
15q25.1
LOCUSID
ALIAS
HsT19268,NEDMEHM
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10588
MIM: 604197
HGNC: 7437
Ensembl: ENSG00000136371
Variants:
dbSNP: 10588
ClinVar: 10588
TCGA: ENSG00000136371
COSMIC: MTHFS
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000136371 | ENST00000258874 | P49914 |
| ENSG00000136371 | ENST00000559722 | A0A0U1RQM3 |
| ENSG00000136371 | ENST00000560261 | H3BMB9 |
| ENSG00000136371 | ENST00000560919 | H3BN04 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 21895484 | 2012 | The impact of 5,10-methenyltetrahydrofolate synthetase polymorphism on diabetic nephropathy in the Taiwanese population. | 1 |
| 21895484 | 2012 | The impact of 5,10-methenyltetrahydrofolate synthetase polymorphism on diabetic nephropathy in the Taiwanese population. | 1 |
| 19936946 | 2010 | Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer. | 25 |
| 20570913 | 2010 | Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium. | 15 |
| 20634891 | 2010 | Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. | 28 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 19936946 | 2010 | Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer. | 25 |
| 20570913 | 2010 | Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium. | 15 |
| 20634891 | 2010 | Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. | 28 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 18830263 | 2009 | Polymorphisms in DNA repair and one-carbon metabolism genes and overall survival in diffuse large B-cell lymphoma and follicular lymphoma. | 16 |
| 19048631 | 2009 | Oral facial clefts and gene polymorphisms in metabolism of folate/one-carbon and vitamin A: a pathway-wide association study. | 23 |
| 19161160 | 2009 | An association study of 45 folate-related genes in spina bifida: Involvement of cubilin (CUBN) and tRNA aspartic acid methyltransferase 1 (TRDMT1). | 35 |
| 18830263 | 2009 | Polymorphisms in DNA repair and one-carbon metabolism genes and overall survival in diffuse large B-cell lymphoma and follicular lymphoma. | 16 |
| 19048631 | 2009 | Oral facial clefts and gene polymorphisms in metabolism of folate/one-carbon and vitamin A: a pathway-wide association study. | 23 |
Citation
Dessen P
MTHFS (methenyltetrahydrofolate synthetase)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/70550/mthfs-(methenyltetrahydrofolate-synthetase)
