MTMR6 (myotubularin related protein 6)

2014-11-01  

Identity

HGNC
LOCATION
13q12.13
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 9107
MIM: 603561
HGNC: 7453
Ensembl: ENSG00000139505

Variants:

dbSNP: 9107
ClinVar: 9107
TCGA: ENSG00000139505
COSMIC: MTMR6

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000139505ENST00000381801Q9Y217

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Inositol phosphate metabolismKEGGko00562
Phosphatidylinositol signaling systemKEGGko04070
Inositol phosphate metabolismKEGGhsa00562
Phosphatidylinositol signaling systemKEGGhsa04070
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
PI MetabolismREACTOMER-HSA-1483255
Synthesis of PIPs at the plasma membraneREACTOMER-HSA-1660499

References

Pubmed IDYearTitleCitations
383307972024Myotubularin-related protein 6 is an ion channel-associated pro-leishmanial phosphatase.0
383307972024Myotubularin-related protein 6 is an ion channel-associated pro-leishmanial phosphatase.0
318941072019MiR-506-3p suppresses the proliferation of ovarian cancer cells by negatively regulating the expression of MTMR6.17
318941072019MiR-506-3p suppresses the proliferation of ovarian cancer cells by negatively regulating the expression of MTMR6.17
245915802014Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis.56
245915802014Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis.56
231888202013Phosphatidylinositol 3-phosphatase myotubularin-related protein 6 (MTMR6) is regulated by small GTPase Rab1B in the early secretory and autophagic pathways.27
231888202013Phosphatidylinositol 3-phosphatase myotubularin-related protein 6 (MTMR6) is regulated by small GTPase Rab1B in the early secretory and autophagic pathways.27
190389702009MTMR9 increases MTMR6 enzyme activity, stability, and role in apoptosis.23
190389702009MTMR9 increases MTMR6 enzyme activity, stability, and role in apoptosis.23
168473152006Phosphatidylinositol-3 phosphatase myotubularin-related protein 6 negatively regulates CD4 T cells.23
168473152006Phosphatidylinositol-3 phosphatase myotubularin-related protein 6 negatively regulates CD4 T cells.23
126461342003Phosphatidylinositol-5-phosphate activation and conserved substrate specificity of the myotubularin phosphatidylinositol 3-phosphatases.72
128472862003Identification of myotubularin as the lipid phosphatase catalytic subunit associated with the 3-phosphatase adapter protein, 3-PAP.33
126461342003Phosphatidylinositol-5-phosphate activation and conserved substrate specificity of the myotubularin phosphatidylinositol 3-phosphatases.72

Citation

Dessen P

MTMR6 (myotubularin related protein 6)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70559/mtmr6-(myotubularin-related-protein-6)