Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 136319
MIM: 606484
HGNC: 15667
Ensembl: ENSG00000105887
Variants:
dbSNP: 136319
ClinVar: 136319
TCGA: ENSG00000105887
COSMIC: MTPN
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000105887 | ENST00000393085 | P58546 |
| ENSG00000105887 | ENST00000393085 | Q69YG1 |
| ENSG00000105887 | ENST00000435723 | C9JL85 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33439151 | 2021 | Crystal structure of human V-1 in the apo form. | 1 |
| 34170484 | 2021 | The ATO/miRNA-885-5p/MTPN axis induces reversal of drug-resistance in cholangiocarcinoma. | 2 |
| 33439151 | 2021 | Crystal structure of human V-1 in the apo form. | 1 |
| 34170484 | 2021 | The ATO/miRNA-885-5p/MTPN axis induces reversal of drug-resistance in cholangiocarcinoma. | 2 |
| 32483895 | 2020 | Lysyl oxidase suppresses the inflammatory response in anterior cruciate ligament fibroblasts and promotes tissue regeneration by targeting myotrophin via the nuclear factor-kappa B pathway. | 6 |
| 32483895 | 2020 | Lysyl oxidase suppresses the inflammatory response in anterior cruciate ligament fibroblasts and promotes tissue regeneration by targeting myotrophin via the nuclear factor-kappa B pathway. | 6 |
| 29847807 | 2018 | Allosteric Coupling of CARMIL and V-1 Binding to Capping Protein Revealed by Hydrogen-Deuterium Exchange. | 14 |
| 29847807 | 2018 | Allosteric Coupling of CARMIL and V-1 Binding to Capping Protein Revealed by Hydrogen-Deuterium Exchange. | 14 |
| 28300567 | 2017 | 9-cis Retinoic acid modulates myotrophin expression and its miR in physiological and pathophysiological cell models. | 10 |
| 28300567 | 2017 | 9-cis Retinoic acid modulates myotrophin expression and its miR in physiological and pathophysiological cell models. | 10 |
| 26274321 | 2015 | The Human Myotrophin Variant Attenuates MicroRNA-Let-7 Binding Ability but Not Risk of Left Ventricular Hypertrophy in Human Essential Hypertension. | 2 |
| 26274321 | 2015 | The Human Myotrophin Variant Attenuates MicroRNA-Let-7 Binding Ability but Not Risk of Left Ventricular Hypertrophy in Human Essential Hypertension. | 2 |
| 16982933 | 2006 | An unconventional antigen translated by a novel internal ribosome entry site elicits antitumor humoral immune reactions. | 18 |
| 16982933 | 2006 | An unconventional antigen translated by a novel internal ribosome entry site elicits antitumor humoral immune reactions. | 18 |
| 11971907 | 2002 | Myotrophin/V-1, a protein up-regulated in the failing human heart and in postnatal cerebellum, converts NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. | 17 |
Citation
Dessen P
MTPN (myotrophin)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/70564/mtpn-(myotrophin)
