Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54516
MIM: 613542
HGNC: 21051
Ensembl: ENSG00000112031
Variants:
dbSNP: 54516
ClinVar: 54516
TCGA: ENSG00000112031
COSMIC: MTRF1L
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Organelle biogenesis and maintenance | REACTOME | R-HSA-1852241 |
| Mitochondrial translation | REACTOME | R-HSA-5368287 |
| Mitochondrial translation termination | REACTOME | R-HSA-5419276 |
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA447321 | Depressive Disorder, Major | Disease | ClinicalAnnotation | associated | PD | ||
| PA452229 | antidepressants | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 18429816 | 2008 | HMRF1L is a human mitochondrial translation release factor involved in the decoding of the termination codons UAA and UAG. | 22 |
| 18541145 | 2008 | The human mitochondrial translation release factor HMRF1L is methylated in the GGQ motif by the methyltransferase HMPrmC. | 13 |
| 18978678 | 2008 | Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. | 36 |
| 18429816 | 2008 | HMRF1L is a human mitochondrial translation release factor involved in the decoding of the termination codons UAA and UAG. | 22 |
| 18541145 | 2008 | The human mitochondrial translation release factor HMRF1L is methylated in the GGQ motif by the methyltransferase HMPrmC. | 13 |
| 18978678 | 2008 | Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. | 36 |
| 17803939 | 2007 | mtRF1a is a human mitochondrial translation release factor decoding the major termination codons UAA and UAG. | 61 |
| 17803939 | 2007 | mtRF1a is a human mitochondrial translation release factor decoding the major termination codons UAA and UAG. | 61 |
Citation
Dessen P
MTRF1L (mitochondrial translation release factor 1 like)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/70565/mtrf1l-(mitochondrial-translation-release-factor-1-like)
