MUC3B (mucin 3B, cell surface associated)

2014-11-01  

Identity

HGNC
MUC3B
LOCATION
7q22
LOCUSID
57876
ALIAS
MUC3,MUC3A

Other Information

Locus ID:

NCBI: 57876
MIM: 605633
HGNC: 13384

Variants:

dbSNP: 57876
ClinVar: 57876
COSMIC: MUC3B

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
O-linked glycosylationREACTOMER-HSA-5173105
O-linked glycosylation of mucinsREACTOMER-HSA-913709
Termination of O-glycan biosynthesisREACTOMER-HSA-977068
DiseaseREACTOMER-HSA-1643685
Diseases of glycosylationREACTOMER-HSA-3781865
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
C-type lectin receptors (CLRs)REACTOMER-HSA-5621481
Dectin-2 familyREACTOMER-HSA-5621480
Diseases associated with O-glycosylation of proteinsREACTOMER-HSA-3906995
Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)REACTOMER-HSA-5083632
Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)REACTOMER-HSA-5083625
Defective GALNT12 causes colorectal cancer 1 (CRCS1)REACTOMER-HSA-5083636

References

Pubmed IDYearTitleCitations
362566562022Discovery of a MUC3B gene reconstructs the membrane mucin gene cluster on human chromosome 7.2
362566562022Discovery of a MUC3B gene reconstructs the membrane mucin gene cluster on human chromosome 7.2
181635202008Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.7
181635202008Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.7
129583102003Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.4
129583102003Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.4

Citation

Dessen P

MUC3B (mucin 3B, cell surface associated)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70583/muc3b-(mucin-3b-cell-surface-associated)