MYL7 (myosin light chain 7)

2014-11-01  

Identity

HGNC
MYL7
LOCATION
7p13
LOCUSID
58498
ALIAS
MYL2A,MYLC2A
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 58498
MIM: 613993
HGNC: 21719
Ensembl: ENSG00000106631

Variants:

dbSNP: 58498
ClinVar: 58498
TCGA: ENSG00000106631
COSMIC: MYL7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000106631ENST00000223364Q01449
ENSG00000106631ENST00000431007H7C3E3
ENSG00000106631ENST00000431289H7C1B1
ENSG00000106631ENST00000446581H7C482
ENSG00000106631ENST00000447951H7C243
ENSG00000106631ENST00000457314H7BZE4
ENSG00000106631ENST00000457910F8WD94
ENSG00000106631ENST00000458240C9JEG4

Expression (GTEx)

0
1000
2000
3000
4000
5000
6000
7000
8000
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Focal adhesionKEGGko04510
Leukocyte transendothelial migrationKEGGko04670
Regulation of actin cytoskeletonKEGGko04810
Focal adhesionKEGGhsa04510
Leukocyte transendothelial migrationKEGGhsa04670
Regulation of actin cytoskeletonKEGGhsa04810
Muscle contractionREACTOMER-HSA-397014
Smooth Muscle ContractionREACTOMER-HSA-445355

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
187180802008[Expression and function of non-muscle myosin-IIA in Fechtner syndrome].0
187180802008[Expression and function of non-muscle myosin-IIA in Fechtner syndrome].0
128470962003Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform.118
128470962003Functional divergence of human cytoplasmic myosin II: kinetic characterization of the non-muscle IIA isoform.118

Citation

Dessen P

MYL7 (myosin light chain 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70618/myl7-(myosin-light-chain-7)