Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 29116
MIM: 610082
HGNC: 21155
Ensembl: ENSG00000007944
Variants:
dbSNP: 29116
ClinVar: 29116
TCGA: ENSG00000007944
COSMIC: MYLIP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000007944 | ENST00000349606 | Q5TIA5 |
| ENSG00000007944 | ENST00000356840 | Q8WY64 |
Expression (GTEx)
Pathways
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA444516 | Hypercholesterolemia | Disease | ClinicalAnnotation | associated | PD | 25171759 | |
| PA448500 | atorvastatin | Chemical | ClinicalAnnotation | associated | PD | 25171759 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37047406 | 2023 | Mouse Spinal Cord Vascular Transcriptome Analysis Identifies CD9 and MYLIP as Injury-Induced Players. | 1 |
| 37094639 | 2023 | Effect of type 2 diabetes on the inducible degrader of LDL receptor. | 0 |
| 37047406 | 2023 | Mouse Spinal Cord Vascular Transcriptome Analysis Identifies CD9 and MYLIP as Injury-Induced Players. | 1 |
| 37094639 | 2023 | Effect of type 2 diabetes on the inducible degrader of LDL receptor. | 0 |
| 33154164 | 2021 | SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1. | 6 |
| 33185588 | 2021 | Identification of MYLIP gene and miRNA-802 involved in the growth and metastasis of cervical cancer cells. | 12 |
| 33450693 | 2021 | Novel associations of SNPs MYLIP rs3757354 and ABCA1 2230806 gene with early-onset-preeclampsia: A case-control candidate genetic study. | 0 |
| 33845890 | 2021 | Genetic polymorphism of IDOL gene was associated with the susceptibility of coronary artery disease in Han population in Xinjiang, China. | 2 |
| 33154164 | 2021 | SUMOylation of the ubiquitin ligase IDOL decreases LDL receptor levels and is reversed by SENP1. | 6 |
| 33185588 | 2021 | Identification of MYLIP gene and miRNA-802 involved in the growth and metastasis of cervical cancer cells. | 12 |
| 33450693 | 2021 | Novel associations of SNPs MYLIP rs3757354 and ABCA1 2230806 gene with early-onset-preeclampsia: A case-control candidate genetic study. | 0 |
| 33845890 | 2021 | Genetic polymorphism of IDOL gene was associated with the susceptibility of coronary artery disease in Han population in Xinjiang, China. | 2 |
| 32727844 | 2020 | Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site. | 3 |
| 32868861 | 2020 | IDOL gene variant is associated with hyperlipidemia in Han population in Xinjiang, China. | 3 |
| 32727844 | 2020 | Structural analysis of the LDL receptor-interacting FERM domain in the E3 ubiquitin ligase IDOL reveals an obscured substrate-binding site. | 3 |
Citation
Dessen P
MYLIP (myosin regulatory light chain interacting protein)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/70619/mylip-(myosin-regulatory-light-chain-interacting-protein)
