NAGPA (N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase)

2014-11-01  

Identity

HGNC
LOCATION
16p13.3
LOCUSID
ALIAS
APAA,UCE

Other Information

Locus ID:

NCBI: 51172
MIM: 607985
HGNC: 17378
Ensembl: ENSG00000103174

Variants:

dbSNP: 51172
ClinVar: 51172
TCGA: ENSG00000103174
COSMIC: NAGPA

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000103174ENST00000312251Q9UK23
ENSG00000103174ENST00000381955Q9UK23
ENSG00000103174ENST00000562037K7EJ25
ENSG00000103174ENST00000562346K7ERI4
ENSG00000103174ENST00000562746Q9UK23
ENSG00000103174ENST00000563578K7EPH3
ENSG00000103174ENST00000565876K7EK96
ENSG00000103174ENST00000569296K7EL75
ENSG00000103174ENST00000649828Q9UK23

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
LysosomeKEGGko04142
LysosomeKEGGhsa04142

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
339932322022Identification of a shared genetic risk locus for Kawasaki disease and immunoglobulin A vasculitis by a cross-phenotype meta-analysis.8
339932322022Identification of a shared genetic risk locus for Kawasaki disease and immunoglobulin A vasculitis by a cross-phenotype meta-analysis.8
321093652020Crystal Structure of the Mannose-6-Phosphate Uncovering Enzyme.4
321093652020Crystal Structure of the Mannose-6-Phosphate Uncovering Enzyme.4
310030072019Genetic factors and therapy outcomes in persistent developmental stuttering.5
310030072019Genetic factors and therapy outcomes in persistent developmental stuttering.5
292896112018Variants in GNPTAB, GNPTG and NAGPA genes are associated with stutterers.9
292896112018Variants in GNPTAB, GNPTG and NAGPA genes are associated with stutterers.9
256437702015Association study of stuttering candidate genes GNPTAB, GNPTG and NAGPA with dyslexia in Chinese population.4
256437702015Association study of stuttering candidate genes GNPTAB, GNPTG and NAGPA with dyslexia in Chinese population.4
235725272013Structure and function of the DUF2233 domain in bacteria and in the human mannose 6-phosphate uncovering enzyme.4
235725272013Structure and function of the DUF2233 domain in bacteria and in the human mannose 6-phosphate uncovering enzyme.4
228849632012A role for inherited metabolic deficits in persistent developmental stuttering.11
228849632012A role for inherited metabolic deficits in persistent developmental stuttering.11
219561092011Analysis of mannose 6-phosphate uncovering enzyme mutations associated with persistent stuttering.10

Citation

Dessen P

NAGPA (N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70675/nagpa-(n-acetylglucosamine-1-phosphodiester-alpha-n-acetylglucosaminidase)