NDOR1 (NADPH dependent diflavin oxidoreductase 1)

2014-11-01  

Identity

HGNC
NDOR1
LOCATION
9q34.3
LOCUSID
27158
ALIAS
CIAE1,NR1,bA350O14.9
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 27158
MIM: 606073
HGNC: 29838
Ensembl: ENSG00000188566

Variants:

dbSNP: 27158
ClinVar: 27158
TCGA: ENSG00000188566
COSMIC: NDOR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000188566ENST00000371521Q9UHB4
ENSG00000188566ENST00000427047Q9UHB4
ENSG00000188566ENST00000458322Q9UHB4

Expression (GTEx)

0
5
10
15
20
25
30
35
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Cytosolic iron-sulfur cluster assemblyREACTOMER-HSA-2564830

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
235962122013Molecular view of an electron transfer process essential for iron-sulfur protein biogenesis.26
235962122013Molecular view of an electron transfer process essential for iron-sulfur protein biogenesis.26
211520632010Characterisation of the expression of NMDA receptors in human astrocytes.75
211520632010Characterisation of the expression of NMDA receptors in human astrocytes.75
126312752003Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1.14
128719382003Redundancy in the pathway for redox regulation of mammalian methionine synthase: reductive activation by the dual flavoprotein, novel reductase 1.12
126312752003Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1.14
128719382003Redundancy in the pathway for redox regulation of mammalian methionine synthase: reductive activation by the dual flavoprotein, novel reductase 1.12

Citation

Dessen P

NDOR1 (NADPH dependent diflavin oxidoreductase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70752/ndor1-(nadph-dependent-diflavin-oxidoreductase-1)