Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 84504
MIM: 605955
HGNC: 19321
Ensembl: ENSG00000148826
Variants:
dbSNP: 84504
ClinVar: 84504
TCGA: ENSG00000148826
COSMIC: NKX6-2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000148826 | ENST00000368592 | Q9C056 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33009998 | 2021 | NK6 Homeobox 2 Regulated Gastrokin-2 Suppresses Gastric Cancer Cell Proliferation and Invasion via Akt Signaling Pathway. | 2 |
| 33770499 | 2021 | One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2. | 13 |
| 33009998 | 2021 | NK6 Homeobox 2 Regulated Gastrokin-2 Suppresses Gastric Cancer Cell Proliferation and Invasion via Akt Signaling Pathway. | 2 |
| 33770499 | 2021 | One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2. | 13 |
| 31509304 | 2020 | Genetic and phenotypic characterization of NKX6-2-related spastic ataxia and hypomyelination. | 8 |
| 32004679 | 2020 | Expanding the clinical and neuroimaging features of NKX6-2-related hereditary spastic ataxia type 8. | 0 |
| 32246862 | 2020 | A homozygous missense variant in the homeobox domain of the NKX6-2 results in progressive spastic ataxia type 8 associated with lower limb weakness and neurological manifestations. | 3 |
| 31509304 | 2020 | Genetic and phenotypic characterization of NKX6-2-related spastic ataxia and hypomyelination. | 8 |
| 32004679 | 2020 | Expanding the clinical and neuroimaging features of NKX6-2-related hereditary spastic ataxia type 8. | 0 |
| 32246862 | 2020 | A homozygous missense variant in the homeobox domain of the NKX6-2 results in progressive spastic ataxia type 8 associated with lower limb weakness and neurological manifestations. | 3 |
| 29388673 | 2018 | Expanding the clinical and genetic spectra of NKX6-2-related disorder. | 2 |
| 29388673 | 2018 | Expanding the clinical and genetic spectra of NKX6-2-related disorder. | 2 |
| 28575651 | 2017 | Mutations in NKX6-2 Cause Progressive Spastic Ataxia and Hypomyelination. | 20 |
| 28969374 | 2017 | Biallelic mutations in the homeodomain of NKX6-2 underlie a severe hypomyelinating leukodystrophy. | 9 |
| 28575651 | 2017 | Mutations in NKX6-2 Cause Progressive Spastic Ataxia and Hypomyelination. | 20 |
Citation
Dessen P
NKX6-2 (NK6 homeobox 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/70860/nkx6-2-(nk6-homeobox-2)
