NLRP10 (NLR family pyrin domain containing 10)

2014-11-01  

Identity

HGNC
NLRP10
LOCATION
11p15.4
LOCUSID
338322
ALIAS
CLR11.1,NALP10,NOD8,PAN5,PYNOD

Other Information

Locus ID:

NCBI: 338322
MIM: 609662
HGNC: 21464
Ensembl: ENSG00000182261

Variants:

dbSNP: 338322
ClinVar: 338322
TCGA: ENSG00000182261
COSMIC: NLRP10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182261ENST00000328600Q86W26
ENSG00000182261ENST00000526590E9PPY0

Expression (GTEx)

0
1
2
3
4
5
6
7
8
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
370430732024NLRP10 promotes AGEs-induced NLRP1 and NLRP3 inflammasome activation via ROS/MAPK/NF-κB signaling in human periodontal ligament cells.0
370430732024NLRP10 promotes AGEs-induced NLRP1 and NLRP3 inflammasome activation via ROS/MAPK/NF-κB signaling in human periodontal ligament cells.0
350786902022Association of HLA-DPB1, NLRP10, OVOL1, and ABCC11 with the axillary microbiome in a Japanese population.0
350786902022Association of HLA-DPB1, NLRP10, OVOL1, and ABCC11 with the axillary microbiome in a Japanese population.0
305100712019NLRP10 Affects the Stability of Abin-1 To Control Inflammatory Responses.7
305100712019NLRP10 Affects the Stability of Abin-1 To Control Inflammatory Responses.7
295015742018Cigarette smoke-induced inflammation: NLRP10-mediated mechanisms.11
295015742018Cigarette smoke-induced inflammation: NLRP10-mediated mechanisms.11
287669902017Involvement of NLRP10 in IL-1α induction of oral epithelial cells by periodontal pathogens.4
287669902017Involvement of NLRP10 in IL-1α induction of oral epithelial cells by periodontal pathogens.4
235626142013Roles of NLRP10 in innate and adaptive immunity.9
235626142013Roles of NLRP10 in innate and adaptive immunity.9
223659662012Functional characterization of the p53 binding site in the human PYNOD promoter.1
226722332012NLRP10 enhances Shigella-induced pro-inflammatory responses.17
223659662012Functional characterization of the p53 binding site in the human PYNOD promoter.1

Citation

Dessen P

NLRP10 (NLR family pyrin domain containing 10)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70871/nlrp10-(nlr-family-pyrin-domain-containing-10)