NLRP14 (NLR family pyrin domain containing 14)

2014-11-01  

Identity

HGNC
LOCATION
11p15.4
LOCUSID
ALIAS
CLR11.2,GC-LRR,NALP14,NOD5,PAN8
FUSION GENES

Other Information

Locus ID:

NCBI: 338323
MIM: 609665
HGNC: 22939
Ensembl: ENSG00000158077

Variants:

dbSNP: 338323
ClinVar: 338323
TCGA: ENSG00000158077
COSMIC: NLRP14

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000158077ENST00000299481Q86W24

Expression (GTEx)

0
1
2

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380603822023NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance.0
380603822023NLRP14 deficiency causes female infertility with oocyte maturation defects and early embryonic arrest by impairing cytoplasmic UHRF1 abundance.0
284233392017Germ-Cell-Specific Inflammasome Component NLRP14 Negatively Regulates Cytosolic Nucleic Acid Sensing to Promote Fertilization.25
284233392017Germ-Cell-Specific Inflammasome Component NLRP14 Negatively Regulates Cytosolic Nucleic Acid Sensing to Promote Fertilization.25
254030122015Intrinsic flexibility of NLRP pyrin domains is a key factor in their conformational dynamics, fold stability, and dimerization.12
254030122015Intrinsic flexibility of NLRP pyrin domains is a key factor in their conformational dynamics, fold stability, and dimerization.12
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
204031352010The genetics of NOD-like receptors in Crohn's disease.34
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
204031352010The genetics of NOD-like receptors in Crohn's disease.34
190748852008Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.32
190748852008Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.32
169318012006Mutations in the testis-specific NALP14 gene in men suffering from spermatogenic failure.26
169318012006Mutations in the testis-specific NALP14 gene in men suffering from spermatogenic failure.26

Citation

Dessen P

NLRP14 (NLR family pyrin domain containing 14)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70875/nlrp14-(nlr-family-pyrin-domain-containing-14)