NMUR1 (neuromedin U receptor 1)

2014-11-01  

Identity

HGNC
LOCATION
2q37.1
LOCUSID
ALIAS
(FM-3),FM-3,FM3,GPC-R,GPR66,NMU1R
FUSION GENES

Other Information

Locus ID:

NCBI: 10316
MIM: 604153
HGNC: 4518
Ensembl: ENSG00000171596

Variants:

dbSNP: 10316
ClinVar: 10316
TCGA: ENSG00000171596
COSMIC: NMUR1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000171596ENST00000305141Q9HB89

Expression (GTEx)

0
1
2
3
4
5
6

Pathways

PathwaySourceExternal ID
Neuroactive ligand-receptor interactionKEGGko04080
Neuroactive ligand-receptor interactionKEGGhsa04080
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR ligand bindingREACTOMER-HSA-500792
Class A/1 (Rhodopsin-like receptors)REACTOMER-HSA-373076
Peptide ligand-binding receptorsREACTOMER-HSA-375276
GPCR downstream signalingREACTOMER-HSA-388396
G alpha (i) signalling eventsREACTOMER-HSA-418594
G alpha (q) signalling eventsREACTOMER-HSA-416476
Gastrin-CREB signalling pathway via PKC and MAPKREACTOMER-HSA-881907

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380717532024Neuromedin U regulates the anti-tumor activity of CD8(+) T cells and glycolysis of tumor cells in the tumor microenvironment of pancreatic ductal adenocarcinoma in an NMUR1-dependent manner.3
383780052024Expression of NMU and NMUR1 in tryptase-positive mast cells and PBLs in allergic rhinitis patients' nasal mucosa.0
380717532024Neuromedin U regulates the anti-tumor activity of CD8(+) T cells and glycolysis of tumor cells in the tumor microenvironment of pancreatic ductal adenocarcinoma in an NMUR1-dependent manner.3
383780052024Expression of NMU and NMUR1 in tryptase-positive mast cells and PBLs in allergic rhinitis patients' nasal mucosa.0
362325392022Increased NMUR1 Expression in Mast Cells in the Synovial Membrane of Obese Osteoarthritis Patients.6
362325392022Increased NMUR1 Expression in Mast Cells in the Synovial Membrane of Obese Osteoarthritis Patients.6

Citation

Dessen P

NMUR1 (neuromedin U receptor 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/70890/nmur1-(neuromedin-u-receptor-1)