Identity
HGNC
LOCATION
17q25.1
LOCUSID
ALIAS
DNT,DNT1,HEL74,P5N2,PN-I,PN-II,UMPH2,cdN,dNT-1
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 30833
MIM: 191720
HGNC: 17144
Ensembl: ENSG00000125458
Variants:
dbSNP: 30833
ClinVar: 30833
TCGA: ENSG00000125458
COSMIC: NT5C
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA449748 | gemcitabine | Chemical | Pathway | associated | 25162786 | ||
| PA450163 | lamivudine | Chemical | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 20877624 | 2010 | Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. | 20 |
| 12714505 | 2003 | Molecular characterization of Turkish patients with pyrimidine 5' nucleotidase-I deficiency. | 2 |
| 12714505 | 2003 | Molecular characterization of Turkish patients with pyrimidine 5' nucleotidase-I deficiency. | 2 |
| 12418222 | 2002 | Kinetic evidence for covalent phosphoryl-enzyme intermediate in phosphotransferase activity of human red cell pyrimidine nucleotidases. | 0 |
| 12418222 | 2002 | Kinetic evidence for covalent phosphoryl-enzyme intermediate in phosphotransferase activity of human red cell pyrimidine nucleotidases. | 0 |
Citation
Dessen P
NT5C (5, 3-nucleotidase, cytosolic)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/70995/nt5c-(5-3-nucleotidase-cytosolic)
