NUDT12 (nudix hydrolase 12)

2014-11-01  

Identity

HGNC
LOCATION
5q21.2
LOCUSID
ALIAS
-

Other Information

Locus ID:

NCBI: 83594
MIM: 609232
HGNC: 18826
Ensembl: ENSG00000112874

Variants:

dbSNP: 83594
ClinVar: 83594
TCGA: ENSG00000112874
COSMIC: NUDT12

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112874ENST00000230792Q9BQG2
ENSG00000112874ENST00000507423Q9BQG2
ENSG00000112874ENST00000507423E7EM93

Expression (GTEx)

0
5
10
15

Pathways

PathwaySourceExternal ID
Nicotinate and nicotinamide metabolismKEGGko00760
Nicotinate and nicotinamide metabolismKEGGhsa00760
PeroxisomeKEGGko04146
PeroxisomeKEGGhsa04146
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of vitamins and cofactorsREACTOMER-HSA-196854
Metabolism of water-soluble vitamins and cofactorsREACTOMER-HSA-196849
Nicotinate metabolismREACTOMER-HSA-196807
Nicotinamide salvagingREACTOMER-HSA-197264

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
311019192019Structural and mechanistic basis of mammalian Nudt12 RNA deNADding.27
318755502019Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs.13
311019192019Structural and mechanistic basis of mammalian Nudt12 RNA deNADding.27
318755502019Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs.13
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
127907962003Mammalian NADH diphosphatases of the Nudix family: cloning and characterization of the human peroxisomal NUDT12 protein.33
127907962003Mammalian NADH diphosphatases of the Nudix family: cloning and characterization of the human peroxisomal NUDT12 protein.33

Citation

Dessen P

NUDT12 (nudix hydrolase 12)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71016/nudt12-(nudix-hydrolase-12)