Identity
HGNC
LOCATION
6p21.31
LOCUSID
ALIAS
DIPP,DIPP-1,DIPP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 11165
MIM: 609228
HGNC: 8050
Ensembl: ENSG00000272325
Variants:
dbSNP: 11165
ClinVar: 11165
TCGA: ENSG00000272325
COSMIC: NUDT3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000272325 | ENST00000607016 | O95989 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism | REACTOME | R-HSA-1430728 |
| Inositol phosphate metabolism | REACTOME | R-HSA-1483249 |
| Synthesis of pyrophosphates in the cytosol | REACTOME | R-HSA-1855167 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37466765 | 2024 | Uterine leiomyoma with RAD51B::NUDT3 fusion: a report of 2 cases. | 0 |
| 37466765 | 2024 | Uterine leiomyoma with RAD51B::NUDT3 fusion: a report of 2 cases. | 0 |
| 33475202 | 2021 | New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1. | 8 |
| 34788624 | 2021 | Polyphosphate degradation by Nudt3-Zn(2+) mediates oxidative stress response. | 16 |
| 33475202 | 2021 | New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1. | 8 |
| 34788624 | 2021 | Polyphosphate degradation by Nudt3-Zn(2+) mediates oxidative stress response. | 16 |
| 32093658 | 2020 | Disentangling the genetics of sarcopenia: prioritization of NUDT3 and KLF5 as genes for lean mass & HLA-DQB1-AS1 for hand grip strength with the associated enhancing SNPs & a scoring system. | 14 |
| 32727897 | 2020 | InsP(7) is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics. | 15 |
| 32093658 | 2020 | Disentangling the genetics of sarcopenia: prioritization of NUDT3 and KLF5 as genes for lean mass & HLA-DQB1-AS1 for hand grip strength with the associated enhancing SNPs & a scoring system. | 14 |
| 32727897 | 2020 | InsP(7) is a small-molecule regulator of NUDT3-mediated mRNA decapping and processing-body dynamics. | 15 |
| 26932476 | 2016 | Nudt3 is an mRNA decapping enzyme that modulates cell migration. | 29 |
| 26932476 | 2016 | Nudt3 is an mRNA decapping enzyme that modulates cell migration. | 29 |
| 23708086 | 2013 | NUDT3 rs206936 is associated with body mass index in obese Japanese women. | 5 |
| 23708086 | 2013 | NUDT3 rs206936 is associated with body mass index in obese Japanese women. | 5 |
Citation
Dessen P
NUDT3 (nudix hydrolase 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71027/nudt3-(nudix-hydrolase-3)
