OARD1 (O-acyl-ADP-ribose deacylase 1)

2014-11-01  

Identity

HGNC
LOCATION
6p21.1
LOCUSID
ALIAS
C6orf130,TARG1,dJ34B21.3

Other Information

Locus ID:

NCBI: 221443
MIM: 614393
HGNC: 21257
Ensembl: ENSG00000124596

Variants:

dbSNP: 221443
ClinVar: 221443
TCGA: ENSG00000124596
COSMIC: OARD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000124596ENST00000373154C9J5P1
ENSG00000124596ENST00000424266Q9Y530
ENSG00000124596ENST00000424266A0A024RCY9
ENSG00000124596ENST00000463088Q9Y530
ENSG00000124596ENST00000463088A0A024RCY9
ENSG00000124596ENST00000464633C9JA90
ENSG00000124596ENST00000468811Q9Y530
ENSG00000124596ENST00000468811A0A024RCY9
ENSG00000124596ENST00000469104C9IZY1
ENSG00000124596ENST00000471367C9IZY1
ENSG00000124596ENST00000479950Q9Y530
ENSG00000124596ENST00000479950A0A024RCY9
ENSG00000124596ENST00000480585C9J5P1
ENSG00000124596ENST00000482515C9JA90
ENSG00000124596ENST00000482853H7C5Q1
ENSG00000124596ENST00000486443C9JXC3
ENSG00000124596ENST00000488238C9JNE2
ENSG00000124596ENST00000628419C9J5P1

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
345083552021TARG1 protects against toxic DNA ADP-ribosylation.15
345083552021TARG1 protects against toxic DNA ADP-ribosylation.15
324278672020Comparative analysis of MACROD1, MACROD2 and TARG1 expression, localisation and interactome.17
324278672020Comparative analysis of MACROD1, MACROD2 and TARG1 expression, localisation and interactome.17
260913422015Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation.139
260913422015Structures and Mechanisms of Enzymes Employed in the Synthesis and Degradation of PARP-Dependent Protein ADP-Ribosylation.139
234812552013Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease.179
234812552013Deficiency of terminal ADP-ribose protein glycohydrolase TARG1/C6orf130 in neurodegenerative disease.179
218495062011Orphan macrodomain protein (human C6orf130) is an O-acyl-ADP-ribose deacylase: solution structure and catalytic properties.45
218495062011Orphan macrodomain protein (human C6orf130) is an O-acyl-ADP-ribose deacylase: solution structure and catalytic properties.45

Citation

Dessen P

OARD1 (O-acyl-ADP-ribose deacylase 1)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71080/oard1-(o-acyl-adp-ribose-deacylase-1)