Identity
HGNC
LOCATION
10q26.13
LOCUSID
ALIAS
GACR,HOGA,OATASE,OKT
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 4942
MIM: 613349
HGNC: 8091
Ensembl: ENSG00000065154
Variants:
dbSNP: 4942
ClinVar: 4942
TCGA: ENSG00000065154
COSMIC: OAT
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000065154 | ENST00000368845 | P04181 |
| ENSG00000065154 | ENST00000368845 | A0A140VJQ4 |
| ENSG00000065154 | ENST00000539214 | P04181 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38413821 | 2024 | Role of lung ornithine aminotransferase in idiopathic pulmonary fibrosis: regulation of mitochondrial ROS generation and TGF-β1 activity. | 0 |
| 38413821 | 2024 | Role of lung ornithine aminotransferase in idiopathic pulmonary fibrosis: regulation of mitochondrial ROS generation and TGF-β1 activity. | 0 |
| 36834788 | 2023 | Biochemical and Bioinformatic Studies of Mutations of Residues at the Monomer-Monomer Interface of Human Ornithine Aminotransferase Leading to Gyrate Atrophy of Choroid and Retina. | 1 |
| 36991126 | 2023 | Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer. | 25 |
| 36834788 | 2023 | Biochemical and Bioinformatic Studies of Mutations of Residues at the Monomer-Monomer Interface of Human Ornithine Aminotransferase Leading to Gyrate Atrophy of Choroid and Retina. | 1 |
| 36991126 | 2023 | Ornithine aminotransferase supports polyamine synthesis in pancreatic cancer. | 25 |
| 35460691 | 2022 | Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase. | 4 |
| 36098904 | 2022 | Ornithine aminotransferase and carbamoyl phosphate synthetase 1 involved in ammonia metabolism serve as novel targets for early stages of gastric cancer. | 1 |
| 35460691 | 2022 | Determination of the pH dependence, substrate specificity, and turnovers of alternative substrates for human ornithine aminotransferase. | 4 |
| 36098904 | 2022 | Ornithine aminotransferase and carbamoyl phosphate synthetase 1 involved in ammonia metabolism serve as novel targets for early stages of gastric cancer. | 1 |
| 33068755 | 2021 | Deficit of human ornithine aminotransferase in gyrate atrophy: Molecular, cellular, and clinical aspects. | 18 |
| 33243052 | 2021 | A novel c.980C>G variant in OAT results in identifiable gyrate atrophy phenotype associated with retinal detachment in a young female. | 1 |
| 33463379 | 2021 | Variable phenotypes of gyrate atrophy in siblings with a nonsense mutation in OAT gene. | 1 |
| 34097381 | 2021 | Turnover and Inactivation Mechanisms for (S)-3-Amino-4,4-difluorocyclopent-1-enecarboxylic Acid, a Selective Mechanism-Based Inactivator of Human Ornithine Aminotransferase. | 5 |
| 33068755 | 2021 | Deficit of human ornithine aminotransferase in gyrate atrophy: Molecular, cellular, and clinical aspects. | 18 |
Citation
Dessen P
OAT (ornithine aminotransferase)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71083/oat-(ornithine-aminotransferase)
