Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51676
MIM: 605759
HGNC: 16012
Ensembl: ENSG00000100628
Variants:
dbSNP: 51676
ClinVar: 51676
TCGA: ENSG00000100628
COSMIC: ASB2
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 29955039 | 2018 | High-throughput analysis of the RNA-induced silencing complex in myotonic dystrophy type 1 patients identifies the dysregulation of miR-29c and its target ASB2. | 11 |
| 30116272 | 2018 | The notch pathway promotes NF-κB activation through Asb2 in T cell acute lymphoblastic leukemia cells. | 14 |
| 29955039 | 2018 | High-throughput analysis of the RNA-induced silencing complex in myotonic dystrophy type 1 patients identifies the dysregulation of miR-29c and its target ASB2. | 11 |
| 30116272 | 2018 | The notch pathway promotes NF-κB activation through Asb2 in T cell acute lymphoblastic leukemia cells. | 14 |
| 26537633 | 2015 | Substrates of the ASB2α E3 ubiquitin ligase in dendritic cells. | 8 |
| 26537633 | 2015 | Substrates of the ASB2α E3 ubiquitin ligase in dendritic cells. | 8 |
| 24044920 | 2013 | Phosphorylation of serine 323 of ASB2α is pivotal for the targeting of filamin A to degradation. | 3 |
| 24052262 | 2013 | ASB2α, an E3 ubiquitin ligase specificity subunit, regulates cell spreading and triggers proteasomal degradation of filamins by targeting the filamin calponin homology 1 domain. | 10 |
| 24044920 | 2013 | Phosphorylation of serine 323 of ASB2α is pivotal for the targeting of filamin A to degradation. | 3 |
| 24052262 | 2013 | ASB2α, an E3 ubiquitin ligase specificity subunit, regulates cell spreading and triggers proteasomal degradation of filamins by targeting the filamin calponin homology 1 domain. | 10 |
| 22174154 | 2012 | ECSASB2 mediates MLL degradation during hematopoietic differentiation. | 32 |
| 22382022 | 2012 | The ASB2β Ubiquitin-interacting motif is involved in its monoubiquitination. | 1 |
| 22916308 | 2012 | Filamins but not Janus kinases are substrates of the ASB2α cullin-ring E3 ubiquitin ligase in hematopoietic cells. | 5 |
| 22174154 | 2012 | ECSASB2 mediates MLL degradation during hematopoietic differentiation. | 32 |
| 22382022 | 2012 | The ASB2β Ubiquitin-interacting motif is involved in its monoubiquitination. | 1 |
Citation
Dessen P
ASB2 (ankyrin repeat and SOCS box containing 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-12-01
Online version: http://atlasgeneticsoncology.org/gene/711/asb2-(ankyrin-repeat-and-socs-box-containing-2)
