OR2W3 (olfactory receptor family 2 subfamily W member 3)

2014-11-01  

Identity

HGNC
LOCATION
1q44
LOCUSID
ALIAS
OR2W3P,OR2W8P,OST718

Other Information

Locus ID:

NCBI: 343171
MIM: 616729
HGNC: 15021
Ensembl: ENSG00000238243

Variants:

dbSNP: 343171
ClinVar: 343171
TCGA: ENSG00000238243
COSMIC: OR2W3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000238243ENST00000360358Q7Z3T1

Expression (GTEx)

0
5
10
15
20

Pathways

PathwaySourceExternal ID
Olfactory transductionKEGGko04740
Olfactory transductionKEGGhsa04740
Signal TransductionREACTOMER-HSA-162582
Signaling by GPCRREACTOMER-HSA-372790
GPCR downstream signalingREACTOMER-HSA-388396
Olfactory Signaling PathwayREACTOMER-HSA-381753

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
330976662020The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR.10
330976662020The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR.10
279167482017OR2M3: A Highly Specific and Narrowly Tuned Human Odorant Receptor for the Sensitive Detection of Onion Key Food Odorant 3-Mercapto-2-methylpentan-1-ol.23
282620882017Genome-Wide Association Study of Post-Traumatic Stress Disorder in Two High-Risk Populations.9
279167482017OR2M3: A Highly Specific and Narrowly Tuned Human Odorant Receptor for the Sensitive Detection of Onion Key Food Odorant 3-Mercapto-2-methylpentan-1-ol.23
282620882017Genome-Wide Association Study of Post-Traumatic Stress Disorder in Two High-Risk Populations.9
268910082016OR2W3 sequence variants are unlikely to cause inherited retinal diseases.4
268910082016OR2W3 sequence variants are unlikely to cause inherited retinal diseases.4
253743922015Association of single nucleotide polymorphisms in the USF1, GTF2A1L and OR2W3 genes with non-obstructive azoospermia in the Chinese population.2
257834832015Whole-exome sequencing identifies OR2W3 mutation as a cause of autosomal dominant retinitis pigmentosa.12
258478452015Susceptibility to male infertility: replication study in Japanese men looking for an association with four GWAS-derived loci identified in European men.0
253743922015Association of single nucleotide polymorphisms in the USF1, GTF2A1L and OR2W3 genes with non-obstructive azoospermia in the Chinese population.2
257834832015Whole-exome sequencing identifies OR2W3 mutation as a cause of autosomal dominant retinitis pigmentosa.12
258478452015Susceptibility to male infertility: replication study in Japanese men looking for an association with four GWAS-derived loci identified in European men.0

Citation

Dessen P

OR2W3 (olfactory receptor family 2 subfamily W member 3)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71295/or2w3-(olfactory-receptor-family-2-subfamily-w-member-3)