Identity
HGNC
LOCATION
7q22.1
LOCUSID
ALIAS
C7orf19,CBCIP2,MEM142B,TMEM142B
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 80228
MIM: 610929
HGNC: 21667
Ensembl: ENSG00000160991
Variants:
dbSNP: 80228
ClinVar: 80228
TCGA: ENSG00000160991
COSMIC: ORAI2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33310726 | 2021 | ORAI2 Promotes Gastric Cancer Tumorigenicity and Metastasis through PI3K/Akt Signaling and MAPK-Dependent Focal Adhesion Disassembly. | 55 |
| 34857756 | 2021 | Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue. | 19 |
| 33310726 | 2021 | ORAI2 Promotes Gastric Cancer Tumorigenicity and Metastasis through PI3K/Akt Signaling and MAPK-Dependent Focal Adhesion Disassembly. | 55 |
| 34857756 | 2021 | Atlas of RNA editing events affecting protein expression in aged and Alzheimer's disease human brain tissue. | 19 |
| 32722509 | 2020 | ORAI2 Down-Regulation Potentiates SOCE and Decreases Aβ42 Accumulation in Human Neuroglioma Cells. | 12 |
| 32882268 | 2020 | Orai-1 and Orai-2 regulate oral cancer cell migration and colonisation by suppressing Akt/mTOR/NF-κB signalling. | 17 |
| 32896813 | 2020 | Distinct pharmacological profiles of ORAI1, ORAI2, and ORAI3 channels. | 53 |
| 32722509 | 2020 | ORAI2 Down-Regulation Potentiates SOCE and Decreases Aβ42 Accumulation in Human Neuroglioma Cells. | 12 |
| 32882268 | 2020 | Orai-1 and Orai-2 regulate oral cancer cell migration and colonisation by suppressing Akt/mTOR/NF-κB signalling. | 17 |
| 32896813 | 2020 | Distinct pharmacological profiles of ORAI1, ORAI2, and ORAI3 channels. | 53 |
| 31772693 | 2019 | Identification of Key Pathways and Genes in the Orai2 Mediated Classical and Mesenchymal Subtype of Glioblastoma by Bioinformatic Analyses. | 6 |
| 31772693 | 2019 | Identification of Key Pathways and Genes in the Orai2 Mediated Classical and Mesenchymal Subtype of Glioblastoma by Bioinformatic Analyses. | 6 |
| 27865925 | 2017 | Orai1 and Orai2 mediate store-operated calcium entry that regulates HL60 cell migration and FAK phosphorylation. | 29 |
| 29203863 | 2017 | ORAI channels are critical for receptor-mediated endocytosis of albumin. | 22 |
| 27865925 | 2017 | Orai1 and Orai2 mediate store-operated calcium entry that regulates HL60 cell migration and FAK phosphorylation. | 29 |
Citation
Dessen P
ORAI2 (ORAI calcium release-activated calcium modulator 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71544/orai2-(orai-calcium-release-activated-calcium-modulator-2)
