OSBPL10 (oxysterol binding protein like 10)

2014-11-01  

Identity

HGNC
OSBPL10
LOCATION
3p23
LOCUSID
114884
ALIAS
ORP10,OSBP9
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 114884
MIM: 606738
HGNC: 16395
Ensembl: ENSG00000144645

Variants:

dbSNP: 114884
ClinVar: 114884
TCGA: ENSG00000144645
COSMIC: OSBPL10

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144645ENST00000396556Q9BXB5
ENSG00000144645ENST00000428241H7C199
ENSG00000144645ENST00000429492H7C487
ENSG00000144645ENST00000438237Q9BXB5

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Acyl chain remodelling of PSREACTOMER-HSA-1482801

References

Pubmed IDYearTitleCitations
348175322022PI4P/PS countertransport by ORP10 at ER-endosome membrane contact sites regulates endosome fission.25
348175322022PI4P/PS countertransport by ORP10 at ER-endosome membrane contact sites regulates endosome fission.25
314099032019Circular RNA profile identifies circOSBPL10 as an oncogenic factor and prognostic marker in gastric cancer.49
314099032019Circular RNA profile identifies circOSBPL10 as an oncogenic factor and prognostic marker in gastric cancer.49
229064372012ORP10, a cholesterol binding protein associated with microtubules, regulates apolipoprotein B-100 secretion.17
229064372012ORP10, a cholesterol binding protein associated with microtubules, regulates apolipoprotein B-100 secretion.17
202245712010Variation in OSBPL10 is associated with dyslipidemia.7
202245712010Variation in OSBPL10 is associated with dyslipidemia.7
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206108952010Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.17
206108952010Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.17
202245712010Variation in OSBPL10 is associated with dyslipidemia.7
202245712010Variation in OSBPL10 is associated with dyslipidemia.7
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
206108952010Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.17

Citation

Dessen P

OSBPL10 (oxysterol binding protein like 10)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71549/osbpl10-(oxysterol-binding-protein-like-10)