Identity
HGNC
LOCATION
18q11.2
LOCUSID
ALIAS
ORP-1,ORP1,OSBPL1B
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 114876
MIM: 606730
HGNC: 16398
Ensembl: ENSG00000141447
Variants:
dbSNP: 114876
ClinVar: 114876
TCGA: ENSG00000141447
COSMIC: OSBPL1A
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37017523 | 2023 | Host Lipid Transport Protein ORP1 Is Necessary for Coxiella burnetii Growth and Vacuole Expansion in Macrophages. | 2 |
| 37017523 | 2023 | Host Lipid Transport Protein ORP1 Is Necessary for Coxiella burnetii Growth and Vacuole Expansion in Macrophages. | 2 |
| 34504082 | 2021 | ORP1L mediated PI(4)P signaling at ER-lysosome-mitochondrion three-way contact contributes to mitochondrial division. | 28 |
| 34504082 | 2021 | ORP1L mediated PI(4)P signaling at ER-lysosome-mitochondrion three-way contact contributes to mitochondrial division. | 28 |
| 32023146 | 2020 | Oxysterol-binding protein-related protein 1 variants have opposing cholesterol transport activities from the endolysosomes. | 11 |
| 32023146 | 2020 | Oxysterol-binding protein-related protein 1 variants have opposing cholesterol transport activities from the endolysosomes. | 11 |
| 30783101 | 2019 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P(2)/PI(3,4)P(2). | 40 |
| 30783101 | 2019 | Allosteric enhancement of ORP1-mediated cholesterol transport by PI(4,5)P(2)/PI(3,4)P(2). | 40 |
| 30012887 | 2018 | A non-canonical GTPase interaction enables ORP1L-Rab7-RILP complex formation and late endosome positioning. | 13 |
| 30012887 | 2018 | A non-canonical GTPase interaction enables ORP1L-Rab7-RILP complex formation and late endosome positioning. | 13 |
| 27345457 | 2017 | Interactions between the Coxiella burnetii parasitophorous vacuole and the endoplasmic reticulum involve the host protein ORP1L. | 22 |
| 28077646 | 2017 | Adenovirus Modulates Toll-Like Receptor 4 Signaling by Reprogramming ORP1L-VAP Protein Contacts for Cholesterol Transport from Endosomes to the Endoplasmic Reticulum. | 18 |
| 28564600 | 2017 | Oxysterol-Binding Protein-Related Protein 1L Regulates Cholesterol Egress from the Endo-Lysosomal System. | 69 |
| 29039586 | 2017 | A single nucleotide polymorphism located in microRNA-499a causes loss of function resulting in increased expression of osbpl1a and reduced serum HDL level. | 6 |
| 27345457 | 2017 | Interactions between the Coxiella burnetii parasitophorous vacuole and the endoplasmic reticulum involve the host protein ORP1L. | 22 |
Citation
Dessen P
OSBPL1A (oxysterol binding protein like 1A)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71551/osbpl1a-(oxysterol-binding-protein-like-1a)
