Identity
HGNC
LOCATION
7p15.3
LOCUSID
ALIAS
ORP-3,ORP3,OSBP3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26031
MIM: 606732
HGNC: 16370
Ensembl: ENSG00000070882
Variants:
dbSNP: 26031
ClinVar: 26031
TCGA: ENSG00000070882
COSMIC: OSBPL3
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36781118 | 2023 | Oxysterol-binding protein-like 3 is a novel target gene of peroxisome proliferator-activated receptor γ in fatty liver disease. | 0 |
| 37550605 | 2023 | Prognostic and biological function value of OSBPL3 in colorectal cancer analyzed by multi-omic data analysis. | 0 |
| 37740130 | 2023 | Loss of ORP3 induces aneuploidy and promotes bladder cancer cell invasion through deregulated microtubule and actin dynamics. | 1 |
| 36781118 | 2023 | Oxysterol-binding protein-like 3 is a novel target gene of peroxisome proliferator-activated receptor γ in fatty liver disease. | 0 |
| 37550605 | 2023 | Prognostic and biological function value of OSBPL3 in colorectal cancer analyzed by multi-omic data analysis. | 0 |
| 37740130 | 2023 | Loss of ORP3 induces aneuploidy and promotes bladder cancer cell invasion through deregulated microtubule and actin dynamics. | 1 |
| 36517805 | 2022 | The relationships of OSBPL3 expression with KI-67 expression and KRAS mutations in CRC: implications for diagnosis and prognosis. | 4 |
| 36517805 | 2022 | The relationships of OSBPL3 expression with KI-67 expression and KRAS mutations in CRC: implications for diagnosis and prognosis. | 4 |
| 33857182 | 2021 | Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins. | 7 |
| 34584127 | 2021 | Oxysterol binding protein-like 3 (OSBPL3) is a novel driver gene that promotes tumor growth in part through R-Ras/Akt signaling in gastric cancer. | 12 |
| 33857182 | 2021 | Structure of human ORP3 ORD reveals conservation of a key function and ligand specificity in OSBP-related proteins. | 7 |
| 34584127 | 2021 | Oxysterol binding protein-like 3 (OSBPL3) is a novel driver gene that promotes tumor growth in part through R-Ras/Akt signaling in gastric cancer. | 12 |
| 31659255 | 2020 | Aneuploidy-inducing gene knockdowns overlap with cancer mutations and identify Orp3 as a B-cell lymphoma suppressor. | 11 |
| 32234213 | 2020 | Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex. | 30 |
| 32819557 | 2020 | The crystal structure of ORP3 reveals the conservative PI4P binding pattern. | 5 |
Citation
Dessen P
OSBPL3 (oxysterol binding protein like 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71553/osbpl3-(oxysterol-binding-protein-like-3)
