OXSM (3-oxoacyl-ACP synthase, mitochondrial)

2014-11-01  

Identity

HGNC
LOCATION
3p24.2
LOCUSID
ALIAS
CEM1,FASN2D,KASI,KS

Other Information

Locus ID:

NCBI: 54995
MIM: 610324
HGNC: 26063
Ensembl: ENSG00000151093

Variants:

dbSNP: 54995
ClinVar: 54995
TCGA: ENSG00000151093
COSMIC: OXSM

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000151093ENST00000280701Q9NWU1
ENSG00000151093ENST00000280701A0A024R2Q9
ENSG00000151093ENST00000420173Q9NWU1
ENSG00000151093ENST00000428266C9JQQ2
ENSG00000151093ENST00000448177F8VNS3
ENSG00000151093ENST00000452098C9J2G3
ENSG00000151093ENST00000626005F8VNS3

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Fatty acid biosynthesisKEGGko00061
Biotin metabolismKEGGko00780
Fatty acid biosynthesisKEGGhsa00061
Biotin metabolismKEGGhsa00780
Metabolic pathwaysKEGGhsa01100
Fatty acid biosynthesis, elongationKEGGhsa_M00083
Fatty acid biosynthesis, elongationKEGGM00083
Fatty acid metabolismKEGGhsa01212
Fatty acid metabolismKEGGko01212

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
370874612023Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM).4
370874612023Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM).4
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.20
156682562005Cloning, expression, and characterization of the human mitochondrial beta-ketoacyl synthase. Complementation of the yeast CEM1 knock-out strain.34
156682562005Cloning, expression, and characterization of the human mitochondrial beta-ketoacyl synthase. Complementation of the yeast CEM1 knock-out strain.34

Citation

Dessen P

OXSM (3-oxoacyl-ACP synthase, mitochondrial)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71600/oxsm-(3-oxoacyl-acp-synthase-mitochondrial)