PABPC1L (poly(A) binding protein cytoplasmic 1 like)

2014-11-01  

Identity

HGNC
PABPC1L
LOCATION
20q13.12
LOCUSID
80336
ALIAS
C20orf119,EPAB,PABPC1L1,dJ1069P2.3
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80336
HGNC: 15797
Ensembl: ENSG00000101104

Variants:

dbSNP: 80336
ClinVar: 80336
TCGA: ENSG00000101104
COSMIC: PABPC1L

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101104ENST00000217073Q4VXU2
ENSG00000101104ENST00000217074Q4VXU2
ENSG00000101104ENST00000217075Q4VXT5
ENSG00000101104ENST00000255136Q4VXU2
ENSG00000101104ENST00000372822Q4VXT8
ENSG00000101104ENST00000372826H0Y386
ENSG00000101104ENST00000537323Q4VXU2

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
RNA degradationKEGGko03018
RNA degradationKEGGhsa03018
RNA transportKEGGko03013
RNA transportKEGGhsa03013
mRNA surveillance pathwayKEGGko03015
mRNA surveillance pathwayKEGGhsa03015

References

Pubmed IDYearTitleCitations
381779742024Pathogenic missense variation in PABPC1L/EPAB causes female infertility due to oocyte maturation arrest at the germinal vesicle stage.0
383820682024PABPC1L Induces IDO1 to Promote Tryptophan Metabolism and Immune Suppression in Renal Cell Carcinoma.1
381779742024Pathogenic missense variation in PABPC1L/EPAB causes female infertility due to oocyte maturation arrest at the germinal vesicle stage.0
383820682024PABPC1L Induces IDO1 to Promote Tryptophan Metabolism and Immune Suppression in Renal Cell Carcinoma.1
377238342023Identification of nonfunctional PABPC1L causing oocyte maturation abnormalities and early embryonic arrest in female primary infertility.2
377238342023Identification of nonfunctional PABPC1L causing oocyte maturation abnormalities and early embryonic arrest in female primary infertility.2
268433912016The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.6
268433912016The poly(A)-binding protein genes, EPAB, PABPC1, and PABPC3 are differentially expressed in infertile men with non-obstructive azoospermia.6
187160532008Identification and characterization of human embryonic poly(A) binding protein (EPAB).21
187160532008Identification and characterization of human embryonic poly(A) binding protein (EPAB).21

Citation

Dessen P

PABPC1L (poly(A) binding protein cytoplasmic 1 like)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/71612/pabpc1l-(poly(a)-binding-protein-cytoplasmic-1-like)