Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 29993
MIM: 606512
HGNC: 8570
Ensembl: ENSG00000124507
Variants:
dbSNP: 29993
ClinVar: 29993
TCGA: ENSG00000124507
COSMIC: PACSIN1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Vesicle-mediated transport | REACTOME | R-HSA-5653656 |
| Membrane Trafficking | REACTOME | R-HSA-199991 |
| Clathrin-mediated endocytosis | REACTOME | R-HSA-8856828 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36622335 | 2023 | De Novo PACSIN1 Gene Variant Found in Childhood Lupus and a Role for PACSIN1/TRAF4 Complex in Toll-like Receptor 7 Activation. | 2 |
| 36622335 | 2023 | De Novo PACSIN1 Gene Variant Found in Childhood Lupus and a Role for PACSIN1/TRAF4 Complex in Toll-like Receptor 7 Activation. | 2 |
| 34290082 | 2021 | Regulation of Synapse Weakening through Interactions of the Microtubule Associated Protein Tau with PACSIN1. | 4 |
| 34290082 | 2021 | Regulation of Synapse Weakening through Interactions of the Microtubule Associated Protein Tau with PACSIN1. | 4 |
| 30683896 | 2019 | Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport. | 30 |
| 31601944 | 2019 | Curvature induction and sensing of the F-BAR protein Pacsin1 on lipid membranes via molecular dynamics simulations. | 10 |
| 30683896 | 2019 | Investigation of F-BAR domain PACSIN proteins uncovers membrane tubulation function in cilia assembly and transport. | 30 |
| 31601944 | 2019 | Curvature induction and sensing of the F-BAR protein Pacsin1 on lipid membranes via molecular dynamics simulations. | 10 |
| 24205826 | 2014 | Identification of novel human kinases that suppress hepatitis C virus infection. | 1 |
| 24751538 | 2014 | ProSAP1 and membrane nanodomain-associated syndapin I promote postsynapse formation and function. | 24 |
| 24205826 | 2014 | Identification of novel human kinases that suppress hepatitis C virus infection. | 1 |
| 24751538 | 2014 | ProSAP1 and membrane nanodomain-associated syndapin I promote postsynapse formation and function. | 24 |
| 23898200 | 2013 | Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin. | 63 |
| 23898200 | 2013 | Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin. | 63 |
| 22355135 | 2012 | Phosphorylation of syndapin I F-BAR domain at two helix-capping motifs regulates membrane tubulation. | 16 |
Citation
Dessen P
PACSIN1 (protein kinase C and casein kinase substrate in neurons 1)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71624/pacsin1-(protein-kinase-c-and-casein-kinase-substrate-in-neurons-1)
