Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51702
MIM: 606755
HGNC: 18337
Ensembl: ENSG00000142619
Variants:
dbSNP: 51702
ClinVar: 51702
TCGA: ENSG00000142619
COSMIC: PADI3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000142619 | ENST00000375460 | Q9ULW8 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33573274 | 2021 | Peptidylarginine Deiminase Inhibitor Application, Using Cl-Amidine, PAD2, PAD3 and PAD4 Isozyme-Specific Inhibitors in Pancreatic Cancer Cells, Reveals Roles for PAD2 and PAD3 in Cancer Invasion and Modulation of Extracellular Vesicle Signatures. | 15 |
| 33741961 | 2021 | Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation. | 21 |
| 33971157 | 2021 | Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design. | 9 |
| 33573274 | 2021 | Peptidylarginine Deiminase Inhibitor Application, Using Cl-Amidine, PAD2, PAD3 and PAD4 Isozyme-Specific Inhibitors in Pancreatic Cancer Cells, Reveals Roles for PAD2 and PAD3 in Cancer Invasion and Modulation of Extracellular Vesicle Signatures. | 15 |
| 33741961 | 2021 | Citrullination of pyruvate kinase M2 by PADI1 and PADI3 regulates glycolysis and cancer cell proliferation. | 21 |
| 33971157 | 2021 | Structures of human peptidylarginine deiminase type III provide insights into substrate recognition and inhibitor design. | 9 |
| 32098295 | 2020 | Peptidylarginine Deiminase Isozyme-Specific PAD2, PAD3 and PAD4 Inhibitors Differentially Modulate Extracellular Vesicle Signatures and Cell Invasion in Two Glioblastoma Multiforme Cell Lines. | 24 |
| 32098295 | 2020 | Peptidylarginine Deiminase Isozyme-Specific PAD2, PAD3 and PAD4 Inhibitors Differentially Modulate Extracellular Vesicle Signatures and Cell Invasion in Two Glioblastoma Multiforme Cell Lines. | 24 |
| 30763140 | 2019 | Variant PADI3 in Central Centrifugal Cicatricial Alopecia. | 40 |
| 30763140 | 2019 | Variant PADI3 in Central Centrifugal Cicatricial Alopecia. | 40 |
| 26255191 | 2016 | The amount of citrullinated proteins in synovial tissue is related to serum anti-cyclic citrullinated peptide (anti-CCP) antibody levels. | 4 |
| 26616205 | 2016 | Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis. | 7 |
| 27866708 | 2016 | Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome. | 51 |
| 26255191 | 2016 | The amount of citrullinated proteins in synovial tissue is related to serum anti-cyclic citrullinated peptide (anti-CCP) antibody levels. | 4 |
| 26616205 | 2016 | Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis. | 7 |
Citation
Dessen P
PADI3 (peptidyl arginine deiminase 3)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71627/deep-insight-explorer/
