Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 353238
MIM: 610363
HGNC: 20449
Ensembl: ENSG00000276747
Variants:
dbSNP: 353238
ClinVar: 353238
TCGA: ENSG00000276747
COSMIC: PADI6
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000276747 | ENST00000619609 | Q6TGC4 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Chromatin organization | REACTOME | R-HSA-4839726 |
| Chromatin modifying enzymes | REACTOME | R-HSA-3247509 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38656308 | 2024 | Crystal structure of human peptidylarginine deiminase type VI (PAD6) provides insights into its inactivity. | 0 |
| 38656308 | 2024 | Crystal structure of human peptidylarginine deiminase type VI (PAD6) provides insights into its inactivity. | 0 |
| 37220902 | 2023 | Case report: human early embryonic arrest in a consanguineous Chinese family caused by a novel missense variant of PADI6. | 0 |
| 37220902 | 2023 | Case report: human early embryonic arrest in a consanguineous Chinese family caused by a novel missense variant of PADI6. | 0 |
| 34987164 | 2022 | Novel biallelic mutations in PADI6 in patients with early embryonic arrest. | 5 |
| 34987164 | 2022 | Novel biallelic mutations in PADI6 in patients with early embryonic arrest. | 5 |
| 33221824 | 2021 | Biallelic PADI6 variants cause multilocus imprinting disturbances and miscarriages in the same family. | 19 |
| 33583041 | 2021 | Novel pathogenic variants in NLRP7, NLRP5, and PADI6 in patients with recurrent hydatidiform moles and reproductive failure. | 11 |
| 34036456 | 2021 | Two novel mutations in PADI6 and TLE6 genes cause female infertility due to arrest in embryonic development. | 12 |
| 34573423 | 2021 | Genetic Variation in PADI6-PADI4 on 1p36.13 Is Associated with Common Forms of Human Generalized Epilepsy. | 3 |
| 33221824 | 2021 | Biallelic PADI6 variants cause multilocus imprinting disturbances and miscarriages in the same family. | 19 |
| 33583041 | 2021 | Novel pathogenic variants in NLRP7, NLRP5, and PADI6 in patients with recurrent hydatidiform moles and reproductive failure. | 11 |
| 34036456 | 2021 | Two novel mutations in PADI6 and TLE6 genes cause female infertility due to arrest in embryonic development. | 12 |
| 34573423 | 2021 | Genetic Variation in PADI6-PADI4 on 1p36.13 Is Associated with Common Forms of Human Generalized Epilepsy. | 3 |
| 31664658 | 2020 | New biallelic mutations in PADI6 cause recurrent preimplantation embryonic arrest characterized by direct cleavage. | 18 |
Citation
Dessen P
PADI6 (peptidyl arginine deiminase 6)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71628/padi6-(peptidyl-arginine-deiminase-6)
