Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5051
MIM: 602344
HGNC: 8579
Ensembl: ENSG00000158006
Variants:
dbSNP: 5051
ClinVar: 5051
TCGA: ENSG00000158006
COSMIC: PAFAH2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000158006 | ENST00000374282 | Q99487 |
| ENSG00000158006 | ENST00000374284 | Q99487 |
| ENSG00000158006 | ENST00000439092 | Q5SY00 |
| ENSG00000158006 | ENST00000441420 | Q5SY01 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Ether lipid metabolism | KEGG | ko00565 |
| Ether lipid metabolism | KEGG | hsa00565 |
| Metabolic pathways | KEGG | hsa01100 |
| Hemostasis | REACTOME | R-HSA-109582 |
| Platelet homeostasis | REACTOME | R-HSA-418346 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 26791393 | 2016 | "Association between platelet activating factor acetylhydrolase and diabetic retinopathy: Does inflammation affect the retinal status?". | 4 |
| 26791393 | 2016 | "Association between platelet activating factor acetylhydrolase and diabetic retinopathy: Does inflammation affect the retinal status?". | 4 |
| 25707358 | 2015 | Oligomeric state regulated trafficking of human platelet-activating factor acetylhydrolase type-II. | 1 |
| 25707358 | 2015 | Oligomeric state regulated trafficking of human platelet-activating factor acetylhydrolase type-II. | 1 |
| 17157859 | 2008 | Lipoprotein-associated phospholipase A2 concentrations in plasma are associated with the extent of coronary artery disease and correlate to adipose tissue levels of marine n-3 fatty acids. | 8 |
| 17157859 | 2008 | Lipoprotein-associated phospholipase A2 concentrations in plasma are associated with the extent of coronary artery disease and correlate to adipose tissue levels of marine n-3 fatty acids. | 8 |
| 17272759 | 2007 | Neuroprotective role of transgenic PAF-acetylhydrolase II in mouse models of focal cerebral ischemia. | 7 |
| 17272759 | 2007 | Neuroprotective role of transgenic PAF-acetylhydrolase II in mouse models of focal cerebral ischemia. | 7 |
| 16650870 | 2006 | A single nucleotide polymorphism in the plasma PAF acetylhydrolase gene and risk of atherosclerosis in Japanese patients with peripheral artery occlusive disease. | 4 |
| 16650870 | 2006 | A single nucleotide polymorphism in the plasma PAF acetylhydrolase gene and risk of atherosclerosis in Japanese patients with peripheral artery occlusive disease. | 4 |
| 12406338 | 2002 | Identification of platelet-activating factor acetylhydrolase II in human skin. | 19 |
| 12406338 | 2002 | Identification of platelet-activating factor acetylhydrolase II in human skin. | 19 |
| 11294621 | 2001 | Platelet-activating factor acetylhydrolases: broad substrate specificity and lipoprotein binding does not modulate the catalytic properties of the plasma enzyme. | 17 |
| 11294621 | 2001 | Platelet-activating factor acetylhydrolases: broad substrate specificity and lipoprotein binding does not modulate the catalytic properties of the plasma enzyme. | 17 |
Citation
Dessen P
PAFAH2 (platelet activating factor acetylhydrolase 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71629/pafah2-(platelet-activating-factor-acetylhydrolase-2)
