Identity
HGNC
LOCATION
1q25.2
LOCUSID
ALIAS
PAPP-A2,PAPP-E,PAPPE,PLAC3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 60676
HGNC: 14615
Ensembl: ENSG00000116183
Variants:
dbSNP: 60676
ClinVar: 60676
TCGA: ENSG00000116183
COSMIC: PAPPA2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000116183 | ENST00000367661 | Q9BXP8 |
| ENSG00000116183 | ENST00000367662 | Q9BXP8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34476481 | 2022 | Dynamic Changes in Serum IGF-I and Growth During Infancy: Associations to Body Fat, Target Height, and PAPPA2 Genotype. | 4 |
| 34476481 | 2022 | Dynamic Changes in Serum IGF-I and Growth During Infancy: Associations to Body Fat, Target Height, and PAPPA2 Genotype. | 4 |
| 33783375 | 2021 | Associations of plasma PAPP-A2 and genetic variations with salt sensitivity, blood pressure changes and hypertension incidence in Chinese adults. | 8 |
| 34116346 | 2021 | Serum Inhibin-A and PAPP-A2 in the prediction of pre-eclampsia during the first and second trimesters in high-risk women. | 3 |
| 34203285 | 2021 | Genetic Study of IL6, GDF5 and PAPPA2 in Association with Developmental Dysplasia of the Hip. | 7 |
| 34272725 | 2021 | Short stature with low insulin-like growth factor 1 availability due to pregnancy-associated plasma protein A2 deficiency in a Saudi family. | 4 |
| 33783375 | 2021 | Associations of plasma PAPP-A2 and genetic variations with salt sensitivity, blood pressure changes and hypertension incidence in Chinese adults. | 8 |
| 34116346 | 2021 | Serum Inhibin-A and PAPP-A2 in the prediction of pre-eclampsia during the first and second trimesters in high-risk women. | 3 |
| 34203285 | 2021 | Genetic Study of IL6, GDF5 and PAPPA2 in Association with Developmental Dysplasia of the Hip. | 7 |
| 34272725 | 2021 | Short stature with low insulin-like growth factor 1 availability due to pregnancy-associated plasma protein A2 deficiency in a Saudi family. | 4 |
| 31961798 | 2020 | Anthropometric and biochemical correlates of PAPP-A2, free IGF-I, and IGFBP-3 in childhood. | 9 |
| 31994005 | 2020 | Uteroplacental Ischemia Is Associated with Increased PAPP-A2. | 4 |
| 32004755 | 2020 | Netazepide Inhibits Expression of Pappalysin 2 in Type 1 Gastric Neuroendocrine Tumors. | 6 |
| 32739295 | 2020 | Disorders caused by genetic defects associated with GH-dependent genes: PAPPA2 defects. | 8 |
| 32990126 | 2020 | PAPP-A2 and Inhibin A as Novel Predictors for Pregnancy Complications in Women With Suspected or Confirmed Preeclampsia. | 9 |
Citation
Dessen P
PAPPA2 (pappalysin 2)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71656/pappa2-(pappalysin-2)
