Identity
HGNC
LOCATION
3q27.1
LOCUSID
ALIAS
PRO2207,PSARL,PSARL1,PSENIP2,RHBDS1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55486
MIM: 607858
HGNC: 18253
Ensembl: ENSG00000175193
Variants:
dbSNP: 55486
ClinVar: 55486
TCGA: ENSG00000175193
COSMIC: PARL
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35921890 | 2022 | Cleavage of mitochondrial homeostasis regulator PGAM5 by the intramembrane protease PARL is governed by transmembrane helix dynamics and oligomeric state. | 0 |
| 35921890 | 2022 | Cleavage of mitochondrial homeostasis regulator PGAM5 by the intramembrane protease PARL is governed by transmembrane helix dynamics and oligomeric state. | 0 |
| 32144986 | 2020 | Proapoptotic Mitochondrial Carrier Homolog Protein PSAP Mediates Death Receptor 6 Induced Apoptosis. | 4 |
| 32320686 | 2020 | PARL Protease: A Glimpse at Intramembrane Proteolysis in the Inner Mitochondrial Membrane. | 17 |
| 32470650 | 2020 | Accumulation of HAX-1 and PARL in brainstem- and cortical-type Lewy bodies in Parkinson's disease and dementia with Lewy bodies. | 2 |
| 32144986 | 2020 | Proapoptotic Mitochondrial Carrier Homolog Protein PSAP Mediates Death Receptor 6 Induced Apoptosis. | 4 |
| 32320686 | 2020 | PARL Protease: A Glimpse at Intramembrane Proteolysis in the Inner Mitochondrial Membrane. | 17 |
| 32470650 | 2020 | Accumulation of HAX-1 and PARL in brainstem- and cortical-type Lewy bodies in Parkinson's disease and dementia with Lewy bodies. | 2 |
| 29301859 | 2018 | PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. | 43 |
| 29301859 | 2018 | PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. | 43 |
| 28178523 | 2017 | The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism. | 36 |
| 28288130 | 2017 | PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis. | 63 |
| 28641777 | 2017 | Role of PARL-PINK1-Parkin pathway in adipocyte differentiation. | 11 |
| 28813580 | 2017 | Genetic Association of the PARL-ABCC5-HTR3D-HTR3C Locus With Primary Angle-Closure Glaucoma in Chinese. | 6 |
| 28178523 | 2017 | The Mitochondrial Rhomboid Protease PARL Is Regulated by PDK2 to Integrate Mitochondrial Quality Control and Metabolism. | 36 |
Citation
Dessen P
PARL (presenilin associated rhomboid like)
Atlas Genet Cytogenet Oncol Haematol. 2014-11-01
Online version: http://atlasgeneticsoncology.org/gene/71666/parl-(presenilin-associated-rhomboid-like)
